| 淋巴瘤患者静脉血栓栓塞症的研究进展 |
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| 引用本文： | 兰映霞,张翼鷟. 淋巴瘤患者静脉血栓栓塞症的研究进展[J]. 肿瘤防治研究, 2020, 47(11): 885-888. DOI: 10.3971/j.issn.1000-8578.2020.19.1461 |
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| 作者姓名： | 兰映霞 张翼鷟 |
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| 作者单位： | 1. 300060 天津,天津医科大学肿瘤医院血液科,国家肿瘤临床医学研究中心,天津市“肿瘤防治”重点实验室,天津市恶性肿瘤临床医学研究中心; 2. 510060 广州,中山大学肿瘤防治中心儿童肿瘤科,华南肿瘤学国家重点实验室,肿瘤医学协同创新中心 |
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| 摘 要： | 血液恶性肿瘤患者易发生出凝血障碍,以急性白血病为代表,其中淋巴瘤出凝血障碍发生率也较高,凝血异常所致静脉血栓栓塞(VTE)是其死亡主要原因之一。淋巴瘤血栓栓塞症在非霍奇金淋巴瘤中发生率明显高于霍奇金淋巴瘤,VTE的发生可形成凝血瀑布从而促进肿瘤生长,提示患者疾病进展及病情恶化。淋巴瘤VTE发生的危险因素及相关特点可作为临床早期用药干预的依据从而改善患者预后,极大提高患者的生活质量。
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| 关 键 词： | 淋巴瘤 静脉血栓栓塞症 危险因素 治疗 |
| 收稿时间： | 2019-11-25 |
Progress of Venous Thromboembolism in Lymphoma Patients |
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| LAN Yingxia,ZHANG Yizhuo. Progress of Venous Thromboembolism in Lymphoma Patients[J]. Cancer Research on Prevention and Treatment, 2020, 47(11): 885-888. DOI: 10.3971/j.issn.1000-8578.2020.19.1461 |
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| Authors: | LAN Yingxia ZHANG Yizhuo |
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| Affiliation: | 1. Department of Hematology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060,China; 2. State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine; Department of Pediatric Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, China |
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| Abstract: | Hematological malignant tumor patients are prone to coagulation disorders, represented by acute leukemia(AL), and the incidence of lymphoma coagulation disorders is also high and venous thromboembolism (VTE) caused by coagulopathy is one of the main causes of death. The incidence of lymphoma thromboembolism in non-Hodgkin lymphoma(NHL) is significantly higher than that in Hodgkin lymphoma(HL). The occurrence of VTE can form coagulation waterfall and promote tumor growth, indicating the disease progression and deterioration of patients. Risk factors and related characteristics of lymphoma VTE can be used as the basis for early clinical drug intervention to improve the prognosis of patients and greatly improve the quality of life. |
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| Keywords: | Lymphoma Venous thromboembolism Risk factors Therapy |
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