| 耐碳青霉烯类肺炎克雷伯菌医院感染、耐药性及治疗的研究进展 |
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| 引用本文： | 王珊珊,吴忠伟,赵建平.耐碳青霉烯类肺炎克雷伯菌医院感染、耐药性及治疗的研究进展[J].中国抗生素杂志,2020,45(5):428-432. |
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| 作者姓名： | 王珊珊 吴忠伟 赵建平 |
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| 摘 要： | 医院感染的主要病原菌是肠杆菌科细菌。由于临床上对于抗菌药物的不合理使用，使得耐碳青霉烯类肠杆菌科细菌(carbapenem-resistant Enterobacteriaceae，CRE)的检出率不断增加，而耐碳青霉烯类肺炎克雷伯菌(carbapenem-resistant Klebsiella pneumoniae，CRKP)是临床所分离CRE中最为常见的。本文将从CRKP感染现状、影响因素、耐药机制等方面进行介绍，提高人们对CRKP感染的重视和控制，以期对临床治疗CRKP提供有效的抗菌药物及联合治疗方案。
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| 关 键 词： | 碳青霉烯类 肺炎克雷伯菌 医院感染 耐药机制 治疗 /> |
Advances in research on nosocomial infection,drug resistance and treatment of carbapenem-resistant Klebsiella pneumoniae |
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| ang Shan-shan,Wu Zhong-wei and Zhao Jian-ping.Advances in research on nosocomial infection,drug resistance and treatment of carbapenem-resistant Klebsiella pneumoniae[J].Chinese Journal of Antibiotics,2020,45(5):428-432. |
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| Authors: | ang Shan-shan Wu Zhong-wei and Zhao Jian-ping |
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| Abstract: | At present, the main pathogen of nosocomial infections is Enterobacteriaceae. Due to the irrational use of antibacterial drugs in the clinic, the detection rate of carbapenem-resistant Enterobacteriaceae (CRE) is increasing, while carbapenem-resistant Klebsiella pneumoniae (CRKP) is the most common CRE in clinical isolates.This article will introduce the status quo of CRKP infections, influencing factors, drug resistance mechanisms, to improve people’s attention and control of CRKP infection, in order to provide effective antibacterial drugs and clinical combination treatment of CRKP. |
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| Keywords: | Carbapenem Klebsiella pneumoniae Hospital infection Resistance mechanism Treatment |
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