风痰瘀阻型脑梗死患者的中医药干预疗效观察

目的 探讨半夏白术天麻汤合桃仁红花煎治疗风痰瘀阻型脑梗死的疗效及对患者血清总胆固醇(TC)、甘油三酯(TG)的影响,体现中医注重辨证论治的思想及中医药在脑梗死临床治疗中的价值。 方法 选取2015年8月—2018年7月蚌埠市第三人民医院中西医结合科住院治疗的脑梗死患者54例,中医辨病辨证为中风病之风痰瘀阻型,采用随机数字表法将患者分为2组,每组27例。对照组患者给予一般常规治疗,观察组在对照组的基础上加予中药方剂半夏白术汤合桃仁红花煎加减治疗,水煎服,200 mL/次,2次/d,治疗10 d后分别评估2组患者的神经功能、日常生活活动能力及中医症状评分,并观察2组患者的临床疗效及不良反应发生情况。1个月后随访患者并复查血脂,比较2组患者血清中TC、TG水平。 结果 治疗后2组患者神经功能缺损评分、中医症状评分较治疗前均降低,日常生活活动能力评分较治疗前升高,观察组优于对照组(均P<0.05);观察组总有效率(85.19%)高于对照组(55.56%),差异有统计学意义(P<0.05)。治疗1个月后观察组患者的血清TC、TG降低,且优于对照组(均P<0.05)。治疗期间2组患者均未出现明显不良反应。 结论 半夏白术天麻汤合桃仁红花煎治疗风痰瘀阻型脑梗死,可有效改善患者的神经功能缺损程度,提高患者的日常生活能力,降低患者的TC、TG水平,提高临床疗效。 

Observation on therapeutic effect of traditional Chinese medicine intervention in patients with cerebral infarction of wind-phlegm stasis type

Objective To explore the therapeutic effect of Banxia Baizhu Tianma decoction combined with Taoren Honghua Decoction in the treatment of wind phlegm stasis type cerebral infarction and its influence on the total cholesterol(TC) and triglyceride(TG) in the serum of the patients. Methods From August 2015 to July 2018, 54 patients with wind phlegm stasis type cerebral infarction were selected from the Department of Integrated Traditional Chinese and Western Medicine of the Third People's Hospital of Bengbu. The patients were divided into two groups with 27 cases in each group. The patients in the control group were given general routine treatment, while those in the observation group were given Banxia Baizhu Decoction and Taoren Honghua Decoction on the basis of the control group, decoction 200 mL once, twice a day. After 10 days of treatment, the neurological function, activities of daily life and TCM symptom scores of the two groups were evaluated, and the clinical efficacy and adverse reactions of the two groups were observed. One month later, the patients were followed up and their blood lipids were reexamined. Results After treatment, the neurological deficit score and TCM symptom score of the two groups were lower than before treatment, and the daily life activity score was higher than before treatment, the observation group was better than the control group(all P<0.05). The total effective rate of the observation group(85.19%) was higher than the control group(55.56%, P<0.05). One month later, the serum TC and TG in the observation group were lower than those in the control group(all P<0.05). During the treatment, there was no obvious adverse reaction in both groups. Conclusion Banxia Baizhu Tianma decoction combined with Taoren Honghua Decoction in the treatment of wind phlegm stasis type cerebral infarction can effectively improve the degree of neurological deficit, enhance the ability of daily life, reduce the level of TC and TG, and improve the clinical efficacy.