加替沙星序贯疗法和输液疗法治疗老年下呼吸道感染的疗效比较

目的比较观察加替沙星序贯疗法和输液疗法治疗老年下呼吸道感染的临床疗效。方法对2006年7月至2007年7月92例老年下呼吸道感染患者。分别采用加替沙星序贯疗法和输液疗法进行治疗，对比观察两组的临床疗效、恢复指标、细菌清除率及不良反应。结果序贯疗法组与输液疗法组比较。两组在临床疗效、恢复指标（平均退热时间、平均咳嗽消失时间、平均罗音消失时间及平均治愈时间）、细菌清除卒及不良反应等方面差异均无统计学意义（P〉0．05）。结论加替沙星序贯疗法是一安全、有效、经济、方便的治疗方法。值得推广应用。

Comparison of therapeutic effects between gatifloxacin sequential therapy and infusion administration on lower respiratory tract infection in old patients

OBJECTIVE To compare the clinical efficacy of gatifloxacin sequential therapy versus transfusion administration on lower respiratory tract infection in old patients. METHODS From July 2006 to July 2007, 92 cases of old patients were divided into two groups, which were treated with gatifloxacin sequential therapy or transfusion administration. The clinical efficacy, recover indexes, bacterium clearance and adverse effect of the two groups were compared. RESULTS There was no significant difference in clinical efficacy, recover indexes, bacterium clearance and adverse effect between the two groups（P 〉 0.05）. CONCLUSION The gatifloxacin sequential therapy is a safe, effective, economical and easy method in treatment of lower respiratory tract infection in old patients.