25例骨嗜酸性肉芽肿的诊断和治疗

目的：讨论骨嗜酸性肉芽肿的影像学特点及治疗，对该病的诊断、治疗方法和治疗效果进行总结。方法：分析1998年7月至2005年7月本院手术治疗的25例经病理证实的骨嗜酸性肉芽肿患者的临床资料及随访结果。结果：25例患者均经手术治疗。对患者随访8个月至6年，平均随访33个月，复查结果表明患者病灶均明显修复，未见病灶复发。结论：骨嗜酸性肉芽肿的影像学表观多种多样。部分病变有一定的特征性表现，具有诊断价值。外科治疗对该病是一种积极有效的手段。多数患者单纯肿瘤刮除植骨，或者骨水泥填充即可治愈肿瘤．部分患者病变具有较强的侵袭性，结合化疗可以控制肿瘤。

Diagnosis and Treatment of Eosinophilic Granuloma of the Bone

Objective: To discuss and summarize the clinical features and treatment methods for eosinophilic granuloma of the bone. Methods: The data of 25 patients with localized eosinophilic granuloma of bone, treated from July 1998 to May 2005, were retrospectively investigated. Twenty-four cases had solitary symptomatic lesions and one case had multiple lesions on the spine. Results: The mean follow-up period was 33 months. No recurrence was found in any patient and all survived the disease. Conclusion: The physical manifestations of eosinophilic granuloma of bone are varied. Some cases may have a distinctive manifestation and are therefore easier to diagnose. Surgery is currently an effective means of treatment. Lesion curettage and bone graft or bone cement padding can be used effectively for most patients. Chemoradiotherapy can be used to control multiple lesions or recurrent lesions.