| 分化型甲状腺癌131I治疗后扫描的假阳性分析 |
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| 引用本文： | 罗全勇,陈立波,余永利,陆汉魁,朱瑞森. 分化型甲状腺癌131I治疗后扫描的假阳性分析[J]. 中国医学影像技术, 2004, 20(12): 1930-1932 |
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| 作者姓名： | 罗全勇 陈立波 余永利 陆汉魁 朱瑞森 |
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| 作者单位： | 罗全勇（上海交通大学附属第六人民医院核医学科,上海,200233） 陈立波（上海交通大学附属第六人民医院核医学科,上海,200233） 余永利（上海交通大学附属第六人民医院核医学科,上海,200233） 陆汉魁（上海交通大学附属第六人民医院核医学科,上海,200233） 朱瑞森（上海交通大学附属第六人民医院核医学科,上海,200233） |
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| 基金项目： | 本课题受上海市科学技术发展基金项目资助(024119053). |
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| 摘 要： | 目的分析分化型甲状腺癌^131I治疗后扫描假阳性摄取的常见部位和摄取机制。方法分化型甲状腺癌患者346例，口服治疗剂量^131I后7天进行全身^131I扫描，根据临床症状、体征、^131I全身扫描结果、血清Tg水平和其他影像学检查结果，判断^131I的摄取是否为假阳性摄取。结果胃肠道假阳性摄取65例，肺部假阳性摄取12例，双侧乳腺假阳性摄取3例。两侧腋下汗腺假阳性摄取1例，肝脏显影253例。结论^131I治疗后扫描发生假阳性摄取常见部位主要为胃肠道、肺部和肝脏；应注意甄别，避免使患者接受不必要的^131I治疗。
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| 关 键 词： | 甲状腺癌 ^131I 全身扫描 假阳性 |
| 文章编号： | 1003-3289(2004)12-1930-03 |
| 收稿时间： | 2004-07-22 |
| 修稿时间： | 2004-07-22 |
Clinical analysis of false positive 131I therapeutic scan in differentiated thyroid cancer |
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| LUO Quan-yong,CHEN Li-bo,YU Yong-li,LU Han-kui and ZHU Rui-sen. Clinical analysis of false positive 131I therapeutic scan in differentiated thyroid cancer[J]. Chinese Journal of Medical Imaging Technology, 2004, 20(12): 1930-1932 |
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| Authors: | LUO Quan-yong CHEN Li-bo YU Yong-li LU Han-kui ZHU Rui-sen |
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| Affiliation: | Department of Nuclear Medicine, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai 200233, China;Department of Nuclear Medicine, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai 200233, China;Department of Nuclear Medicine, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai 200233, China;Department of Nuclear Medicine, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai 200233, China;Department of Nuclear Medicine, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai 200233, China |
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| Abstract: | Objective To analyze the common sites and mechanism of false positive therapeutic 131I uptake in differentiated thyroid cancer (DTC). Methods Total 346 cases with DTC were examined with whole body 131I scan 7 days after therapeutic 131I administration. Diagnosis of false positive 131I uptake depended on symptoms, signs, 131I scan, serum thyroglobulin and other imaging investigations of the patients. Results Of the 346 cases, 65 cases were with gastrointestinal tract false positive uptake, 1 of which showed Meckel's diverticulum uptake. False positive uptake in lung was found in 12 cases. Three cases showed false positive uptake in bilateral breast, and 1 showed sweat gland uptake in bilateral axilla. Liver false positive uptake was found in 253 cases. Conclusion The common sites of false positive 131I uptake in DTC were gastrointestinal tract, lung and liver. False positive uptake in other sites is uncommon. A systematic approach to the interpretation of 131I whole body scan is suggested in order to prevent unnecessary treatment with 131I. |
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| Keywords: | Thyroid cancer Iodine-131 Whole-body scan False positive |
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