权重适配的布拉格峰展宽方法

目的:提供一种权重适配的布拉格峰展宽（SOBP）方法，得到平滑的展宽布拉格峰。 方法:通过重新拟合质子能量-射程的关系（盖格法则），找出适配函数的函数形式，并对权重进行重新适配，通过求敏感参数k，得到平滑的SOBP，最后用蒙特卡洛程序FLUKA进行验证。 结果:SOBP的形状对参数k比参数P更加敏感，拟合得到4~32 cm的SOBP，中间平坦区偏差不超过±2%，并解决中间区坍塌的问题。 结论:蒙特卡洛模拟检验了权重适配的SOBP方法的有效性。

Weight adaption-based spread-out Bragg peak method

Abstract: Objective To develop a spread-out Bragg peak (SOBP) method using weight adaption for obtaining a smooth spread-out Bragg peak. Methods By refitting the proton rang-energy relation (Geiger’s law), the adaptation function was obtained, and the weight was re-adjusted. The smooth SOBP was obtained by finding the sensitive parameter k, and finally the proposed method was verified by Monte Carlo code FLUKA. Results The shape of SOBP was more sensitive to the parameter k than parameter P. A SOBP of 4-32 cm was obtained, and the deviation in the middle flat region was no more than ±2%, which solved the problem of collapse in the middle region. Conclusion The effectiveness of SOBP method based on weight adaptation is verified with Monte Carlo simulation.