情绪障碍及认知障碍与睡眠呼吸暂停综合征的相关性分析

目的分析情绪障碍（抑郁、焦虑障碍）及认知障碍与睡眠呼吸暂停综合征（SAS）的相关性。方法 2009年12月～2012年12月在本院五官科就诊的120例老年患者,应用多导睡眠图仪（PSG）进行监测,按严重程度分组：对照组（无SAS）30例、轻度组23例、中度组48例、重度组19例,分别应用Zung抑郁自评量表、Zung焦虑自评量表、简易智能精神状态检查量表进行评分,比较各组数据的差异。将同期在本院神经内科就诊的存在情绪障碍的90例患者和存在认知障碍的90例患者,按年龄分组：59岁以下组、60～74岁组、75岁以上组,分别应用Zung抑郁自评量表、Zung焦虑自评量表、简易智能精神状态检查量表进行评分,并应用多导睡眠图仪进行监测,了解是否存在睡眠呼吸暂停综合征及严重程度。结果睡眠呼吸暂停综合征患者,不同严重程度分组间各项量表评分比较差异有统计学意义（P〈0.05）,且评分与睡眠呼吸暂停综合征严重程度呈正相关（P〈0.05）。情绪障碍患者部分并发睡眠呼吸暂停综合征,其发生比例和严重程度与年龄呈正相关（P〈0.05）,而与量表评分无明显关系（P〉0.05）;认知障碍患者多存在睡眠呼吸暂停综合征,其发生比例和严重程度与年龄及量表评分均呈正相关（P〈0.05）。结论睡眠呼吸暂停综合征患者存在情绪障碍和认知障碍。

Analysis of the relativity between mood disorder,cognitive impairment and sleep apnea syndrome

Objective To analyse the relativity between dysthymic disorder（depressive disorder,anxiety disorder）,cognitive disorder and sleep apnea syndrome （SAS）. Methods 120 cases of elderly patients in ophthalmology and otorhino-laryngology department for treated in our hospital from December 2009 to December 2012,used the guide more sleep figure meter （PSG） to monitor the patients,they were divided into four groups according to the severity： the control group （no SAS） in 30 cases, mild group in 23 cases, moderate group in 48 cases, serious groups in 19 cases,used Zong＇s self-rating depression scale,Zong＇s self-rating anxiety scale and mini-mental state examination to assess their diseases.At the same time,divide 90 patients with dysthymic disorder and 90 patients with cognitive impairment into three groups according to the age：under the age of 59 group,between 60 and 74 years old group,more than 75 years old group,used Zong＇s self-rating depression scale,Zong＇s self-rating anxiety scale and mini-mental state examination to assess their diseases,and monitor them by used polysomnography to make sure if they had got sleep apnea syndrome （SAS）.To evaluate their disease severity. Results There were some significant difference in the assessment from the patients with sleep apnea syndrome （P 0.05）.It was found that the high and low pass of score from different groups was in direct proportion to their disease severity （P 0.05）.The occurrence and the severity of the patients with dysthymic disorder and sleep apnea syndrome were in direct proportion to the patients ＇ age （P 0.05）,but no significant difference with the total standard points of the assessments （P 0.05）.Most of the patients with cognitive impairment have sleep apnea syndrome.The occurrence and the severity of these patients ＇ disease were positive correlated with their age and the total standard points of assessments （P 0.05）. Conclusion Patients with sleep apnea appropriate have dysthymic disorder and cognitive impairment.