我院2012年144例药品不良反应报告分析

目的了解本院药品不良反应（ADR）发生的特点及规律,为临床用药提供参考。方法选择本院2012年收集的144例ADR报告,分别从患者年龄、性别、给药剂型、ADR涉及药品种类、涉及器官或系统以及具体临床表现等方面进行分析。结果本院144例ADR中,抗菌药物引起的ADR最为多见,占43.1%,其次为心血管系统用药,占20.8%;给药剂型以注射剂最为常见,占84.0%;临床表现以皮肤损伤为主,占47.9%。结论应重视ADR报告,加强合理用药,减少不良反应事件发生,保证患者用药安全。

Analysis of 144 cases of adverse drug reaction in our hospital

Objective To understand the regularity and characteristics of adverse drug reaction（ADR） of our hospital,in order to provide reference for clinical medication.Methods 144 cases of ADR reports in our hospital in 2012 were selected and analyzed retrospectively in respect of patients’age,sex,drug administration route drug categories,organ and systems involed,clinical manifestations,and so on.Results In the 144 cases of ADR reports,43.1% of ADR was induced by anti-infective drugs.Followed by the cardiovascular system drugs,which accounted for 20.8%.Drug delivery dosage form for injection was the most common（84.0%）.The main symptoms of ADR were skin rash and pruritus,which accounted for47.9%.Conclusion We should pay attention to ADR reports,strengthen the supervision and management of its use,reduce adverse events occurred,to ensure patient’s medication safety.