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Increased frequencies of CD8+ T lymphocytes recognizing wild-type p53-derived epitopes in peripheral blood correlate with presence of epitope loss tumor variants in patients with hepatocellular carcinoma
Authors:Cicinnati Vito R  Zhang Xia  Yu Zhengya  Ferencik Stanislav  Schmitz Klaus J  Dworacki Grzegorz  Kaczmarek Elzbieta  Oldhafer Karl  Frilling Andrea  Baba Hideo A  Schmid Kurt W  Grosse-Wilde Hans  Broelsch Christoph E  DeLeo Albert B  Gerken Guido  Beckebaum Susanne
Affiliation:Department of Gastroenterology and Hepatology, University Hospital Essen, University of Duisburg-Essen, Germany. vito.cicinnati@uni-due.de
Abstract:
Keywords:cytotoxic T lymphocyte  hepatocellular carcinoma  immunotherapy  p53  tumor escape
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