| 血清铁蛋白和铁蛋白/转铁蛋白比值诊断肝癌及慢性肝病的临床意义 |
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| 引用本文： | 吴小翎,沈鼎明. 血清铁蛋白和铁蛋白/转铁蛋白比值诊断肝癌及慢性肝病的临床意义[J]. 重庆医科大学学报, 1986, 0(3) |
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| 作者姓名： | 吴小翎 沈鼎明 |
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| 作者单位： | 重庆医科大学第二医院内科消化组(吴小翎)，重庆医科大学第二医院内科消化组(沈鼎明) |
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| 摘 要： | 本文检测38例肝细胞性肝癌和42例其他肝病患者的血清铁蛋白(SF)和转铁蛋白(TFN),并计算SF/TFN比值。结果证实肝癌组SF增高,SF/TFN亦显著增高,且后者与失代偿性肝硬化组的重叠较少。对肝病患者,如SF/TFN≥4,应考虑恶变可能
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| 关 键 词： | 铁蛋白 转铁蛋白 肝细胞癌 肝硬化 |
THE CLINICAL VALUE OF SERUM FERRITIN AND THE RATIO OF SERUM FERRITIN/TRANSFERRIN IN HEPATOCELLULAR CARCINOMA ANDCHRONIC LIVER DISEASES |
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| Second Hospital Wu Xiaoling. THE CLINICAL VALUE OF SERUM FERRITIN AND THE RATIO OF SERUM FERRITIN/TRANSFERRIN IN HEPATOCELLULAR CARCINOMA ANDCHRONIC LIVER DISEASES[J]. Journal of Chongqing Medical University, 1986, 0(3) |
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| Authors: | Second Hospital Wu Xiaoling |
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| Affiliation: | Second Hospital Wu Xiaoling |
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| Abstract: | Serum ferritin (SF) and transferrin (TFN) level were measured in 38 patients with hepatoce-llular carcinoma (HCC) and in 42 comparable subjects with chronic live diseases, while the ratio of SF/TFN in each group was calculated respectively .Although either SF concentration, or the ratio of SF/TFN in the group of HCC was elevated, the latter was less than the former in the over- lap of the range of concentration between HCC and cirrhosis. We have confirmed that SF as a marker of HCC is useful, but the diagnostic speciality of SF is worse. More valuable parameter in the diagnosis of HCC, specially in that of AFP-negative HCC, is the ratio of SF/TFN. Decreased TFN concentration may reflect the degree of damaged liver,but it has no role in diagnosis of HCC. If SF/TFN ratio of a patient with liver disease is>4, diagnosis of the patient would be highly suspected to be HCC |
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| Keywords: | Ferritin Transferrin Hepatocellular Carcinoma Liver cirrhosis |
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