| 慢性丙型肝炎患者血清HCV-RNA水平与抗-HCV抗体和肝纤指标水平相关性分析 |
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| 引用本文： | 赵小英,杨邵华.慢性丙型肝炎患者血清HCV-RNA水平与抗-HCV抗体和肝纤指标水平相关性分析[J].国际检验医学杂志,2015(1):47-48. |
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| 作者姓名： | 赵小英 杨邵华 |
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| 作者单位： | 甘肃省中医院检验科,甘肃兰州,730050 |
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| 摘 要： | 目的探讨丙型肝炎患者RNA水平与抗-HCV抗体和肝纤指标水平的关系。方法收集96例慢性丙型肝炎患者的血清,实时荧光定量PCR测定HCV-RNA和ELISA法检测抗-HCV抗体。化学发光法检测LN、PCⅢ、CⅣ及放免法检测HA。并对抗-HCV抗体、HCV-RNA水平与血清肝纤指标之间的关系进行分析。结果本研究的96例抗-HCV抗体阳性的慢性丙型肝炎患者中,HCV-RNA阳性52例,阳性率为54.2%。随着抗-HCV抗体的S/CO值升高,HCV-RNA检出率也在增高,分别为9.5%、37.1%和92.5%。高病毒载量组与低病毒载量组比较,血清HA、LN、PCⅢ及CⅣ水平的差异无统计学意义(P0.05)。结论慢性丙肝患者HCV-RNA阳性检出率与抗-HCV抗体的S/CO值有关,S/CO值越高,HCV-RNA阳性率越高。而RNA水平与肝纤指标水平没有相关性。
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| 关 键 词： | 肝炎抗体 丙型 肝纤指标 |
Study on correlation between serum HCV-RNA level and Anti-HCV with liver fibrosis indexes in patients with chronic hepatitis C |
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| Zhao Xiaoying,Yang Shaohua.Study on correlation between serum HCV-RNA level and Anti-HCV with liver fibrosis indexes in patients with chronic hepatitis C[J].International Journal of Laboratory Medicine,2015(1):47-48. |
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| Authors: | Zhao Xiaoying Yang Shaohua |
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| Institution: | Zhao Xiaoying;Yang Shaohua;Department of Clinical Laboratory,Gansu Provincial Hospital of Traditional Chinese Medicine; |
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| Abstract: | |
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| Keywords: | hepatitis antibodies C type fibrosis indexes |
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