| 阻塞性黄疸患者手术前后红细胞免疫功能和T淋巴细胞亚群的变化 |
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| 引用本文： | 宋德余,李鲁传,李占元.阻塞性黄疸患者手术前后红细胞免疫功能和T淋巴细胞亚群的变化[J].中国普外基础与临床杂志,1998(2). |
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| 作者姓名： | 宋德余 李鲁传 李占元 |
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| 作者单位： | 河北省衡水市哈励逊国际和平医院普外科，山东医科大学附属医院普外科 |
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| 摘 要： | 为探讨阻塞性黄疸患者免疫功能的变化，采用红细胞Ｃ３ｂ受体花环率、红细胞免疫复合物花环率、肿瘤红细胞花环率及ＣＤ＋３、ＣＤ＋４、ＣＤ＋８细胞作为观测指标，测定了３５例阻塞性黄疸患者免疫功能，并与３０例正常人比较。结果显示：疾病组患者术前红细胞及Ｔ淋巴细胞免疫功能低于正常人（Ｐ＜０．００１），术后５天变化不大，术后１４天较术前１天明显增高（Ｐ＜０．０５），但尚未恢复正常。提示解除胆道梗阻及切除肿瘤有助于阻塞性黄疸患者免疫功能的恢复。
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| 关 键 词： | 红细胞 免疫功能 阻塞性黄疸 手术 |
THE STUDY OF PRE AND POST OPERATIVE ERYTHROCYTE AND T LYMPHOCYTE SUBSETS IMMUNE FUNCTION IN OBSTRUCTIVE JAUNDICE |
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| Song Deyu,Li Luchuan,Li Zhanyuan.THE STUDY OF PRE AND POST OPERATIVE ERYTHROCYTE AND T LYMPHOCYTE SUBSETS IMMUNE FUNCTION IN OBSTRUCTIVE JAUNDICE[J].Chinese Journal of Bases and Clinics In General Surgery,1998(2). |
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| Authors: | Song Deyu Li Luchuan Li Zhanyuan |
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| Institution: | Song Deyu,Li Luchuan,Li Zhanyuan. Department of General Surgery,The Affiliated Hospital of Shandong Medical University |
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| Abstract: | In order to study the immune function of patients with obstructive jaundice, the rate of RBC C 3b receptor rosette (RCR), tumour RBC rosettes (TRR), RBC immune complex rosette (RICR) and CD 3,CD 4,CD 8 cells were investigated. In these patients, the pre operative erythrocyte and T lymphocyte subsets immune functions were lower than those of the control ( P <0.001). At the 5th day after operation, there was no significant change and 14th day after operation the erythrocyte and T lymphocyte substes immune functions were significantly elevated( P <0.05), while, compared with the normals, which was still depressed in some degree. Operation is useful to the recovery of the immune function in all patients. |
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| Keywords: | Erythrocyte Immunity Obstructive jaundice Operation |
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