纯净水对血脂及相关指标的影响

目的　观察长期饮用纯净水对大鼠血脂及相关指标的影响。方法　选取健康成年雌性Wistar大鼠 90只 ,随机分为自来水组、纯净水组和纯净水加镁组 ,全部饲喂基础饲料。每个月大鼠尾静脉采血 1次 ,动态观察TC、TG的变化。实验周期 5个月。实验终期大鼠股动脉采血后宰杀 ,测定血脂 (TC、TG、HDL -c、LDL -c)、Ca2 + 、Mg2 + 、MDA等血液生化学指标。结果　纯净水组大鼠血镁浓度较自来水组和纯净水加镁组明显降低 (P <0 0 5) ,TC、TG、LDL、MDA含量显著增高 (P <0 0 5)。结论　长期饮用纯净水可导致雌性大鼠血镁浓度降低 ,血脂 (TC、TTG、LDL)、MDA含量增高 ,可能间接诱发心血管系统损害

Effects of drinking purified-water on blood lipid and correlative indexes

Objective To examine whether feeding with purified-water for a long time had effects on blood lipid and correlative indexes of rats.Methods Three groups of female rats were included.The rat s were received tap-water,purified-water and purified-water with 0.5?g of magn esium sulfate per liter.All rats were fed with basic food for five months.During this time,blood was drown by way of tail vein at the end of every month for dyn amic determination of TC,TG,HDL-c,LDL-c,Ca 2+ ,Mg 2+ and MDA.Rats were phlebotomized through femora then killed for mesuring TC,TG,HDL,LDL,Ca 2+ ,Mg 2+ at the end of the experiment.Results Purified-water rats had lower Mg 2+ level wh ile higher levels of blood TC,TG,LDL and MDA compared with the other two groups.Conclusion Drinking purfied-water for a long time could r esult in the deficiency of blood Mg 2+ while increasing rat's blood lipid ( TC,TG,LDL) and MDA,which would do harm to the cardiovascular system.