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Mixed germ cell tumor of the pineal gland in a pediatric patient
Authors:Serbeze Kabashi,Ilir Ahmetgjekaj,Edlira Harizi,Fjolla Hyseni,Erisa Kola,Valon Vokshi,Guri Hyseni,Ina Kola,Humza Haroon,Masum Rahman,Kledisa Shemsi,Arlind Decka,Livia Capi,Kaltrina Goç  aj,Juna Musa
Abstract:Tumors of the pineal region are a rare clinical entity, comprising approximately 3%-8% of pediatric tumors. Based on their histopathological features, they are typically classified as pineal parenchymal tumors and germ cell tumors, with the latter being more prevalent. Clinical presentation is heterogeneous, with symptoms arising either due to tumor invasion or compression of adjacent neurovascular structures and increased intracranial pressure. Imaging studies are paramount in evaluating pineal region lesions and establishing an accurate diagnosis, with MRI representing the gold standard. Herein, we present the case of a 16-year-old boy presented with recurrent headaches. A head MRI revealed a pineal gland lesion. Histopathological examination confirmed the diagnosis, and the patient underwent a successful gross total resection (GTR) of the tumor. This case report seeks to draw attention to the elusive clinical presentation and management of this infrequently encountered tumor, as well as emphasize the importance of considering pineal gland tumors in the differential diagnosis of recurrent, chronic headaches in pediatric patients.
Keywords:Pineal   Intracranial germinoma   MRI   Chemotherapy   Radiation
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