气街理论指导针刺对癫痫患者内分泌功能的影响

目的：以针灸“气街”理论为指导，观察针刺对癫痫患者内分泌指标的影响。方法：将60例癫痫患者随机分为针药组和药物组，各30例。药物组常规服用抗癫痫药物丙戊酸钠，针药组在常规药治疗基础上，加用针刺治疗，主穴取人迎、风府、天柱。观察治疗前后癫痫计分及检测血浆总皮质醇（CORT）、雌二醇（E2）、孕酮（Prog）、垂体泌乳素（PRL）水平。结果：2组总有效率均为96．7％，两者差异无显著性意义（P〉0．05）；针药组治疗前癫痫计分（13．58±4．01）分，治疗后（8．30±4．52）分，药物组治疗前癫痫计分（12．97±3．91）分，治疗后（7．86±4．90）分，2组治疗后计分较治疗前有明显改善（P〈0．05）；与药物组治疗后相比，针药组的CORT升高具有显著性意义（P=0．046），E2、PRL和Prog的差异则无显著性意义（P〉0．05），说明针药组在有效控制癫痫发作的同时，能更好的改善患者内分泌功能。结论：气街理论指导针刺是改善癫痫患者内分泌状况的有效方法。

EFFECTS ON ENDOCRINAL FUNCTION TREATED WITH ACUPUNCTURE BASED ON QIJIE THEROY IN EPILEPSY PATIENTS

Objective To explore the effects on endocrinal function treated with acupuncture based on Qijie （the pathway of qi） theory in epilepsy patients. Methods A total of 60 epilepsy patients were randomly divided into acupuncture and medication group （n--30）, and single medication group （n = 30）. Both groups were taken antiepileptic drugs, sodium valproate regularly. The acupoints of Fengfu（风府 GV 16）,TiEmzhu （天柱 BL 10） and Renying （人迎 ST 9） were selected as major points according to Qijie theory （气街理论） in acupuncture and medication group. The plasma levels of cortisol （CORT）, estrogen （E2）, progesterone （Prog）, pituitary prolactin （PRL）, and epilepsy score were observed successively in both enrolled groups in pre-treatment and post-treatment. The outcomes were statistically analyzed. Results The effective rate was 96.7% in either group, and there was no significant differences; the epilepsy score was （13. 584.01） in pre- treatment and （7.86 ___4.90） in post-treatment in acupuncture and medication group and those in single medi- cation group were （12.97 ± 3. 91） and （7. 86 ± 4.90） respectively, indicating apparent improvement （P〈O. 05）. The increase of CORT in acupuncture and medication group indicated significant difference in post-treatment compared with that in single medication group （P = 0.046）. The differences of E2, PRL, Prog in post-treatment in two groups showed no statistical significance （P〉0. 05）. More effects had been a- chieved in acupuncture and medication group on endocrinal function and controlling epileptic seizures in epilepsy patients. Conclusion Acupuncture treatment based on Qijie theory is effective on improving endocrinal function in epilepsy patients.