| Cytotoxicity of Contact Lens Care Solution to Human Corneal Epithelium in Vitro |
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| 引用本文： | Xiangming Gong,Xingwu ZhongDepartment of Optometry,Zhongshan Ophrhalmic Center,Sun Yat-sen University of Medical Sciences,Guangzhou 510060,China. Cytotoxicity of Contact Lens Care Solution to Human Corneal Epithelium in Vitro[J]. 眼科学报, 1998, 14(1): 45-47 |
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| 作者姓名： | Xiangming Gong Xingwu ZhongDepartment of Optometry Zhongshan Ophrhalmic Center Sun Yat-sen University of Medical Sciences Guangzhou 510060 China |
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| 作者单位： | Xiangming Gong，Xingwu ZhongDepartment of Optometry，Zhongshan Ophrhalmic Center，Sun Yat-sen University of Medical Sciences，Guangzhou 510060，China |
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| 摘 要： | Purpose: To investigate the cytotoxicity of soft contact lens multi-purpose care solutions which are now in common use in China.Methods: The cell culture method was used. Cytotoxicity was indicated by significant increases in the number of dead cells relative to controls.Results: Cells were exposed to soft contact lens care solutions for 15 min. They were irregular in shape and variable in size. The intercellular space increased and variable in size.The in-tercelluar space increased and the cells became scrunken. With the time of exposure elongated , damage of cells became more severe.Conclusions: Four kinds of soft contact lens multi-purpose care solutions may have harmful effects on the culture of human corneal epithelial cells. Soaked lenses should be rinsed with saline before being placed in the eyes in order to reduce the potential toxicity of contact lens care solutions. Eye science 1998; 14 :45 - 47.
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| 关 键 词： | 细胞毒素 隐形眼镜 保护液 角膜上皮细胞 |
Cytotoxicity of Contact Lens Care Solution to Human Corneal Epithelium in Vitro |
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| Xiangming Gong Xingwu Zhong. Cytotoxicity of Contact Lens Care Solution to Human Corneal Epithelium in Vitro[J]. Eye science, 1998, 14(1): 45-47 |
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| Authors: | Xiangming Gong Xingwu Zhong |
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| Affiliation: | Department of Optometry, Zhongshan Ophrhalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China. |
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| Abstract: | Purpose: To investigate the cytotoxicity of soft contact lens multi-purpose care solutions which are now in common use in China.Methods: The cell culture method was used. Cytotoxicity was indicated by significant increases in the number of dead cells relative to controls.Results: Cells were exposed to soft contact lens care solutions for 15 min. They were irregular in shape and variable in size. The intercellular space increased and variable in size.The in-tercelluar space increased and the cells became scrunken. With the time of exposure elongated , damage of cells became more severe.Conclusions: Four kinds of soft contact lens multi-purpose care solutions may have harmful effects on the culture of human corneal epithelial cells. Soaked lenses should be rinsed with saline before being placed in the eyes in order to reduce the potential toxicity of contact lens care solutions. Eye science 1998; 14 :45 - 47. |
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| Keywords: | contact lens care solutions cytotoxicity human corneal epithelial cells cell culture |
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