生物胶联合OK-432和平阳霉素治疗面颈部巨大静脉畸形

目的：评价生物胶联合OK-432和平阳霉素治疗面颈部巨大静脉畸形的临床疗效。方法：26例面颈部巨大静脉畸形患者,男11例,女15例;年龄4～23岁,平均年龄11.8岁。通过注射生物胶联合OK-432和平阳霉素进行治疗。所有病例均只接受1次治疗。结果：除术区2～3周肿胀外,均无严重并发症出现。随诊6～12个月（平均8.4个月）,19例治愈,5例显效,2例有效,无无效病例。结论：生物胶联合OK-432和平阳霉素经皮硬化术治疗面颈部巨大静脉畸形,效果良好,并且简单、安全和可靠。

Percutaneous sclerotherapy of massive venous malformations of the face and neck using fibrin glue combined with OK-432 and pingyangmycin

PURPOSE：To evaluate the clinical curative effect of percutaneous sclerotherapy of massive venous malformations of the face and neck using fibrin glue combined with OK-432 and pingyangmycin.METHODS：Twentysix patients with massive venous malformations of the face and neck region（13 males and 15 females;mean age：11.8 years,range：4-23 years） were treated with an injection of fibrin glue combined with OK-432 and pingyangmycin.All lesions received one treatment.RESULTS：All the patients had extreme swelling postoperatively for a period of 2 to 3 weeks without major complications.The follow-up period ranged from 6 to 12 months（median：8.4 months）.Nineteen lesions were completely involuted,five lesions were mostly involuted,and two lesions were partially involuted.None of the lesions showed minimal involution or non-involution.CONCLUSIONS：Percutaneous sclerotherapy using fibrin glue combined with OK-432 and pingyangmycin provides a simple,safe,and reliable alternative treatment for massive venous malformations of the face and neck.