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二膦酸盐与颌骨骨坏死
引用本文:贺捷,邱蔚六.二膦酸盐与颌骨骨坏死[J].中国口腔颌面外科杂志,2010,8(4):370-375.
作者姓名:贺捷  邱蔚六
作者单位:上海交通大学医学院附属第九人民医院·口腔医学院,口腔颌面外科,上海,200011
摘    要:自从Marx等2003年首次报道二膦酸盐类药物可导致颌骨骨坏死以来,与二膦酸盐相关的颌骨骨坏死逐渐引起了临床医师的关注。本文就二膦酸盐相关性颌骨骨坏死的诊断标准及流行病学、病因学、临床表现、预防和治疗现状作一综述。

关 键 词:二膦酸盐  颌骨骨坏死  骨质疏松症  病因学  预防  治疗

Bisphosphonate and osteonecrosis of the jaw
HE Jie,QIU Wei-liu.Bisphosphonate and osteonecrosis of the jaw[J].China Journal of Oral and Maxillofacial Surgery,2010,8(4):370-375.
Authors:HE Jie  QIU Wei-liu
Institution:.(Department of Oral and Maxillofacial Surgery,College of Stomatology,Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine.Shanghai 200011,China)
Abstract:Since Marx et al first reported that osteonecrosis of the jaw was possibly associated with the use of bisphosphonates in 2003,more and more attentions were given to this new complication.This article summarized the diagnostic criteria,epidemiology,etiology,clinical manifestation,prevention and treatment of the bisphosphonate-related osteonecrosis of the jaw.
Keywords:Bisphosphonate  Osteonecrosis of the jaw  Osteoporosis  Etiology  Prevention  Treatment
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