本溪市城区2型糖尿病合并脑卒中患病率及其相关因素分析

目的了解本溪市中心城区的2型糖尿病患者合并脑卒中的患病率及其相关因素。方法对常住本溪市中心城区且参加城镇职工基本医疗保险并建立健康档案的2276例2型糖尿病门诊患者进行问卷调查、体格检查及实验室检测,并根据临床特征及伴有糖尿病其他并发症分组,应用SPSS13.0软件进行统计分析。结果 2型糖尿病合并脑卒中患病率为15.91%。男性患病率(19.64%)高于女性(11.98%),差异有统计学意义(χ2=24.932,P0.05)。随年龄增长和病程延长其患病率呈上升趋势(χ2=54.552,P0.05;χ2=22.785,P0.05)。吸烟(21.65%)、有糖尿病家族史(18.14%)、体质指数(BMI)≥24kg/m2(20.22%)、HbA1C≥8%(19.77%)、高血压(20.61%)、血脂异常(19.28%)、高尿酸血症(24.12%)、伴有冠心病(18.45%)的糖尿病患者合并脑卒中的患病率高于无相关因素者(分别为13.82%,14.02%,9.14%,14.18%,10.49%,6.15%,14.32%,14.90%)差异有统计学意义(P0.05)。Logistic回归分析结果显示,年龄OR(95%CI)为1.833(1.564～2.037);病程1.649(1.259～2.048);性别1.795(1.341～1.969);吸烟1.723(1.337～1.925);糖尿病家族史1.359(1.139～1.901);BMI≥24kg/m22.518(1.886～2.846),HbA1C≥8%1.492(1.236～1.918);高血压2.214(1.685～2.535);血脂异常3.393(2.717～3.633);高尿酸血症1.902(1.314～2.157);冠心病1.292(1.116～1.998)。结论年龄、病程、性别、吸烟、糖尿病家族史、BMI≥24kg/m2、HbA1C≥8%、高血压、血脂异常、高尿酸血症、伴有冠心病是2型糖尿病合并脑卒中的危险因素。

Prevalence of Type 2 Diabetes Mellitus Complicated Stroke and its Risk Factors in Urban Area of Benxi City during 2008 to 2009

Objective To understand the prevalence of type 2 diabetes mellitus complicated stroke and its risk factors. Methods Questionnaire survey and other clinical data from physical examination and laboratory test of 2276 patients with type 2 diabetes mellitus （T2DM）, living in the urban area of Benxi city, were collected. Grouping was based on different clinic characteristics and other complicating diseases. Statistical analysis was carried with SPSS 13.0 software. Results The prevalence of type 2 diabetes mellitns complicated stroke was 15.91% male＇s （19.64%） higher than female＇s （11.98%）, X2=24.932,P〈0.05], which was increased with age and the duration of DM （x2=54.552, P〈0.05; x2=22.785, P〈0.05）. The prevalence of complicated stroke was higher in T2DM patients with smoking （21.65%）, diabetes family history （18.14%）, BMI≥24 kg/m2 （20.22%）, HbA1c≥ 8% （19.77%）, hypertension （20.61%）, hyperlipidemia （18.20%）, hyperurieemia （24.12%）, and coronary heart disease （18.46%） than those without these factors （prevalent rates were 13.82%, 14.02%, 9.14%, 14.18%, 10.49%, 6.15%, 14.32%, 14.88%, respectively. all P〈0.05）. The logistic regression analysis result showed that ORs （95%CIs） were 1.833 （ 1.564-2.037 ）for age, 1.649 （ 1.259- 2.048）for duration of disease, 1.795（1.341-1.969） for gender, 1.723（1.337-1.925）for smoking, 1.359（ 1.139-1.901 ）for family history of DM, 2.518 （1.886-2.846）for BMI ≥24 kg/m2, 1.492 （1.236-1.918）for HbA1c ≥8%, 2.214 （1.685-2.535）for hypertension, 3.393 （2.717-3.633）for hyperlipidemia, 1.902（ 1.314-2.157 ）for hyperuricemia and 1.292（ 1.116-1.998 ）for CHD. Conclusion Old age, longer duration of diabetes, man, smoking, family history of diabetes, BMI ≥24 kg/m2, HbA1c ≥8%, hypertension, hyperlipidemia, hyperurieemia and coronary heart disease may be the risk factors for stroke in T2DM.