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儿童癫痫及抗癫痫治疗对血脂水平影响的研究
引用本文:黄瑞雅,刘运广.儿童癫痫及抗癫痫治疗对血脂水平影响的研究[J].临床神经病学杂志,1996,9(5):268-269.
作者姓名:黄瑞雅  刘运广
作者单位:广西右江民族医学院附属医院神经内科 儿科
摘    要:对114例儿童癫痫患者的血脂水平进行监测。结果发现癫痫本身对血脂水平无影响,抗癫痫药物治疗后总胆固醇和甘油三产高,且随治疗时间的延长差异更为明显,高密度脂蛋白无变化。丙戊酸钠对血脂无影响,而苯舀英钠,苯巴比舀,卡马西平可使TC,TG明显升高。

关 键 词:癫痫  血脂  动脉硬化  抗癫痫药物  儿童  治疗

The research on the Blood lipid level effect by epitepsy and antiepileptic therapy in children.
Huang Ruiya,Liu Yunguang.The research on the Blood lipid level effect by epitepsy and antiepileptic therapy in children.[J].Journal of Clinical Neurology,1996,9(5):268-269.
Authors:Huang Ruiya  Liu Yunguang
Institution:Huang Ruiya,Liu Yunguang.Department of Neuropsychiatry and pediatries,Affiliated Hospital,Youjiang Medical College for National Minorities,Baise,Guangxi 533000.
Abstract:The levels of blood lipid in 114 epileptic children were examined.The results showed that epilepsy itself did not influence the levels of blood lipid,but the total cholesterol (TC) and triglycerid (TG) were significantly increased after antieptleptic therapy ( P <0.001) High density lipoprotein (HDL) did not changed.Although sodium valproate (VPA) did not influence the level of blood lipid,sodium (PHT) phenytoin phenobarbitalum (PB) and carbamazepin (CBZ) could increased TC and TG significantly.The results suggest that the routine surveillance of blood lipid in epileptic children should be done during the antiepileptic therapy,and the suitable alimentary therapy is the key to prevent the adult arteriosclerosis.
Keywords:Epilepsy  Blood  lipid  Arteriosclerosis  Antiepileptic drugs
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