| 灰黄霉素在含共溶剂丙酮的超临界CO2中溶解度的测定和关联 |
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| 引用本文： | 胡国勤,蔡建国,陈鸿雁,邓修. 灰黄霉素在含共溶剂丙酮的超临界CO2中溶解度的测定和关联[J]. 中国医药工业杂志, 2004, 35(2): 81-84 |
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| 作者姓名： | 胡国勤 蔡建国 陈鸿雁 邓修 |
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| 作者单位： | 1. 华东理工大学化学工程研究所,上海,200237;郑州大学化工学院,河南,郑州,450003
2. 华东理工大学化学工程研究所,上海,200237 |
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| 摘 要： | 动态法测定了灰黄霉素在不同的操作温度、压力以及共溶剂丙酮浓度下在超临界CO2中的溶解度.用修正的PR状态方程关联了三元系统的溶解度模型,效果较好.
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| 关 键 词： | 灰黄霉素 超临界流体 共溶剂 溶解度 关联 测定 |
| 文章编号： | 1001-8255(2004)02-0081-04 |
Measurement and correlation of solubility of griseofulvin in supercritical CO2 with acetone as cosolvent |
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| HU Guo-Qin,,CAI Jian-Guo,CHEN Hong-Yan,DENG Xiu. Measurement and correlation of solubility of griseofulvin in supercritical CO2 with acetone as cosolvent[J]. , 2004, 35(2): 81-84 |
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| Authors: | HU Guo-Qin CAI Jian-Guo CHEN Hong-Yan DENG Xiu |
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| Affiliation: | HU Guo-Qin1,2,CAI Jian-Guo1,CHEN Hong-Yan1*,DENG Xiu1 |
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| Abstract: | The solubility of griseofulvin in supercritical CO2 with cosolvent acetone at different temperature,pressure and concentration was measured in this study. The modified PR-EOS was successfully used to correlate the solubi-lity of griseofulvin in this tertiary system. |
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| Keywords: | griseofulvin supercritical fluid cosolvent solubility correlation |
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