148例重症急性胰腺炎的治疗结果分析

目的　分析重症急性胰腺炎 (severeacutepancreatitis,SAP)的治疗方式与疗效的关系。方法　对 1985年 1月～ 2 0 0 2年 6月收治的 148例SAP进行回顾性分析。结果　早期手术组、延期手术组和非手术治疗组的并发症发生率分别为 82 4%、36 4%和 31 9% ,病死率分别为 30 9%、12 1%和 12 8%。早期手术组与后两组比较 ,并发症发生率有非常显著差异 (P <0 .0 1) ,病死率有显著差异 (P <0 .0 5 )。早期手术组和延期手术组再手术率分别为5 1 5 %和 15 2 % ,两组比较有非常显著差异 (P <0 .0 1)。结论　SAP的治疗方式是影响疗效的重要因素 ,应避免在急性反应期手术 ,而尽量采用非手术或延期手术治疗。

Outcome analysis of 148 patients with severe acute pancreatitis

Objective To explore the effect of therapic selection on outcome of patients with severe acute pancreatitis(SAP).Method 148 cases with SAP were analyzed retrospectively.Result The incidences of complications was 82.4%,36.4% and 31.9% for in early-operation group,delayed-operation group and nonoperation group respectively,while the mortality was 30.9%,12.1% and 12.8%,respectively.Compared with the other two groups,the incidences of complications and the mortality in early-operation group was significantly increased (P<0.01 or P<0.05).The reoperation rates were 51.5% in early-operation group,and 15.2% in delayed-operation group,respectively.There was also significant difference (P<0.01) between the two groups.Conclusion Conservative treatment or delayed operation if necessary is preferable than early operation.=