| 抗纤溶药对家兔颅脑损伤后血浆D-二聚体的影响及意义 |
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| 引用本文： | 张胡金,丁辉. 抗纤溶药对家兔颅脑损伤后血浆D-二聚体的影响及意义[J]. 陕西医学杂志, 2009, 38(5) |
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| 作者姓名： | 张胡金 丁辉 |
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| 作者单位： | 1. 西安市中心医院神经外科,西安,710003
2. 西安市中心医院心内科,西安,710003 |
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| 摘 要： | 目的:探讨抗纤溶药对家兔颅脑损伤后血浆D-二聚体变化的影响及意义。方法:制作家兔颅脑损伤模型,分为对照组及药物观察组,分别测定伤后不同时段各项血浆D-二聚体,进行比较。结果:给药组血浆D-二聚体从伤后6h以后均低于对照组(P<0.01)。结论:使用抗纤溶药,可改善因脑损伤而引发的纤溶亢进,达到治疗颅脑损伤的目的。
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| 关 键 词： | 脑损伤/血液 脑损伤/药物疗法 聚合物/代谢 抗纤维蛋白溶解药/治疗应用 模型,动物 兔 |
Effects and significance of antifibrinolytic agents on serum D-Dimer after craniocerebral injury in rabbits |
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| Zhang Hujin,Ding Hui. Effects and significance of antifibrinolytic agents on serum D-Dimer after craniocerebral injury in rabbits[J]. Shaanxi Medical Journal, 2009, 38(5) |
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| Authors: | Zhang Hujin Ding Hui |
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| Abstract: | Objective:To explore the effects and significance of antifibrinolytic agents on serum D-Dimer after craniocerebral injury in rabbits.Methods:Craniocerebral injury model was established.Rabbits were divided randomly into medication group and the control.Serum D-Dimer was determined in different periods after injury for comparison.Results:The serum D-Dimer level was lower in the control in 6 h after injury(P<0.05).Conclusion:Anti fibrinolytic medication can improve hyperfibrinolysis after injury and cure craniocerebral injury. |
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| Keywords: | Brain injury/blood Brain injury/drug therapy Polymers/metabolism Antifibranolytic agent/therapeutic use Model animals Rabbits |
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