Recordings of the optical intrinsic signal from the middle turbinate in response to olfactory and trigeminal stimulation: a pilot study |
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| Authors: | Tadashi Ishimaru Mandy Scheibe Volker Gudziol Simona Negoias |
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| Affiliation: | 1. Department of Otorhinolaryngology, Smell and Taste Clinic, University of Dresden Medical School (“Technische Universit?t Dresden”), Dresden, Germany
2. Hyotan-machi ENT Clinic, Hyotan-machi, 2-13, 920-0845, Kanazawa, Japan
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| Abstract: | Responses from the middle turbinate elicited by olfactory and trigeminal stimuli were studied using the intrinsic optical signal (IOS) recording technique. Nasal cavity was illuminated by 617 nm light. Olfactory (H(2)S) or trigeminal (CO(2)) stimuli of 5-s duration were presented using a computer-controlled olfactometer; IOS responses were captured by a special camera. Averages across five individual IOS recordings were analyzed. When the nasal cavity was exposed to H(2)S, a significant change of the IOS was found; responses to CO(2) were even more pronounced. The present results argue for the idea that the IOS is an indicator of intranasal chemosensory activation. |
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| Keywords: | Smell Olfaction Trigeminal Mucosa Middle turbinate |
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