踝臂指数在老年下肢外周动脉病患者治疗中的临床意义

【目的】探讨踝臂指数（ankle—brachialindex，ABI）在老年下肢外周动脉病患者治疗中应用的临床意义。【方法】老年下肢外周动脉病患者142例，分为2组：A组（单纯药物治疗组）85例，B组（介入治疗＋药物治疗组）57例。A组和B组所有病例联合使用瑞舒伐他汀（10mg／d）、福辛普利钠（10mg／d）、西洛他唑（200mg／d）、拜阿司匹林（100mg／d），连续用药至少12个月。详细记录每位患者的临床资料。并分别于治疗前、治疗后1、3、6、12个月测ABI。【结果】老年下肢外周动脉病患者治疗前ABI〈0．90。B组治疗后1、3、6、12个月的ABI较治疗前明显提高（P〈O．05）。A组治疗后1、3、6、12个月的ABI与治疗前相比无明显变化（P〉0．05）。【结论】ABI是早期诊断老年下肢外周动脉病的无创检查方法，应成为治疗中的常规检查以评估和指导治疗。

Clinical application on the ankle-brachial index in the treatment of peripheral arterial disease in aged patients

[Objective] To investigate the clinical application of ankle-brachial index in the treatment of peripheral arterial disease in aged patients. [Methods] 142 aged patients with peripheral arterial disease were divided into two groups randomly, groupA（n = 85, drug treatment）, groupB（n = 57, interventional therapy and drug treatment）. All the patients were checked for ABI by automatic analysis system of angiosclerosis. [ Results] ABI 〈 0.90 in old patients with peripheral arterial disease before therapy. ABI was not increased in aged patients with peripheral arterial disease after interventional therapy and drug treatment（P 〈 0.05）. ABI is non-increased in old tients with peripheral arterial disease after drug treatment（P 〉 0.05）. [Conclusion] ABI is significant in aged patients with peripheral arterial disease who had taken the interventional therapy.