| 细胞间粘附分子在翼状胬肉中的表达及意义 |
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| 引用本文： | 黄伟奇,杨锦荣,朱朝花,刘凌.细胞间粘附分子在翼状胬肉中的表达及意义[J].中国基层医药,2005,12(3):326-327. |
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| 作者姓名： | 黄伟奇 杨锦荣 朱朝花 刘凌 |
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| 作者单位： | 524001,广东,湛江,广东医学院附属医院眼科 |
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| 摘 要： | 目的 研究翼状胬肉组织中细胞间粘附分子1(ICAM-1)的表达水平,探讨ICAM-1在翼状胬肉病理过程中的作用。方法 采用酶联免疫吸附试验法(ELISA)检测28例翼状胬肉患者组织匀浆中的ICAM-1含量,并与正常人结膜组织进行对照。结果 翼状胬肉组织匀浆中ICAM-1含量明显高于正常对照组(P<0.01),进行期组的ICAM-1含量明显高于静止期组(P<0.05)。结论 在翼状胬肉组织中存在ICAM-1异常表达,可能是翼状胬肉发病的重要原因之一。
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| 关 键 词： | 翼状胬肉 ICAM-1 细胞间粘附分子 含量 异常表达 细胞问粘附分子 酶联免疫吸附试验法 结论 意义 目的 |
| 修稿时间： | 2004年7月26日 |
Expression of ICAM-1 in pterygium and its significance |
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| HUANG Wei-qi,YANG Jin-rong,ZHU Chao-hua,LIU Ling.Expression of ICAM-1 in pterygium and its significance[J].Chinese Journal of Primary Medicine and Pharmacy,2005,12(3):326-327. |
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| Authors: | HUANG Wei-qi YANG Jin-rong ZHU Chao-hua LIU Ling |
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| Abstract: | Objective To evaluate the expression and role of intercellular adhesion molecule-1(ICAM-1) in pterygium.Methods The ELISA were performed to determine the expression of ICAM-1 in 28 patients with primary pterygium,compared to normal conjunctival epithelium.Results The levels of ICAM-1 in pterygium was significantly higher than that in the normal groups(P<0.01),and there was a significant difference between progressive cases and quiescent cases(P<0.05).Conclusion The expression of ICAM-1 is increased in pterygium.The abnormal expression of ICAM-1 may be a positive factor in pathogenesis of pterygium. |
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| Keywords: | Pterygium Conjunctiva Intercellular adhesion molecule-1 |
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