Short-term impact of alcohol detoxification on facial emotions recognition |
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Institution: | 1. Louvain Experimental Psychopathology research group (LEP), Psychological Sciences Research Institute, UCLouvain, Louvain-la-Neuve, Belgium;2. Stanford University, Department of Psychiatry and Behavioral Sciences, Stanford, CA, USA;3. Univ. Lille, Inserm, CHU Lille, U1172 - LilNCog - Lille Neuroscience & Cognition, Lille, France;4. CHU Lille, Clinique de Psychiatrie, CURE, Lille, France;5. Centre National de Ressources et de Résilience Lille-Paris (CN2R), Lille, France;6. Department of Adult Psychiatry, Saint-Luc Academic Hospital & Institute of Neuroscience, UCLouvain, Brussels, Belgium;7. Centre de Neurosciences Cognitives, UMR 5229, CNRS, Bron, France;8. Service Universitaire de Réhabilitation, SUR-CL3R, Centre Hospitalier Le Vinatier, Lyon, France |
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Abstract: | Background and aimsAlcohol use disorder (AUD) is associated with impaired social cognition, including the disturbance of facial emotion recognition (FER). Previous studies have focused on the assessment of basic emotions decoding among patients with AUD, but the evolution of these performances in the early phase of alcohol withdrawal remains unknown.MethodsThis study was based on evolution of social cognition over a period of 21 days in two groups of individuals: a group of 20 AUD patients and a control group of 25 healthy individuals. AUD patients were tested on admission in a detoxification ward and after a 3-week stay. We evaluated FER with the Reading the Mind in the Eyes Test (RMET). We assessed empathy with a multidimensional questionnaire, the Interpersonal Reactivity Index (IRI). We measured anxiety and depression through the self-rating scale Hospital Anxiety and Depression (HAD). We hypothesized that FER would be impaired in AUD patients on admission and improve after detoxification, while being stable in the control group.ResultsRMET scores on admission and at discharge were inferior in AUD patients to those observed in HC (P = 2 × 10?6 and P = 0.033, respectively). In the patient group, the RMET score improved over the stay (P = 0.034). A time-by-group interaction for RMET score was observed (P = 0.003). IRI scores on admission were superior in AUD patients (P = 0.023) whichwas no longer observed at discharge (P = 0.54). This suggests that RMET might be more accurate in measuring theory of mind evolution in AUD patients after withdrawal. HAD scores on admission and at discharge were inferior in AUD patients compared to controls (P = 3 × 10?5 and P = 0.007, respectively). After controlling for HAD initial score, a time-by-group interaction was still observed for RMET scores (P = 0.026).ConclusionFER is impaired in patients with Alcohol Use Disorder compared to controls. This alteration improves after alcohol detoxification. We suggest the RMET could be used to follow the improvement of FER during the first month of abstinence, especially as RMET performance has been associated with maintenance of alcohol withdrawal. |
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Keywords: | Alcohol withdrawal Social cognition Reading the mind in the eyes test Sevrage en alcool Cognitions sociales Reconnaissance des émotions faciales RMET FER"} {"#name":"keyword" "$":{"id":"kw0045"} "$$":[{"#name":"text" "_":"Facial Emotions Recognition EFE"} {"#name":"keyword" "$":{"id":"kw0055"} "$$":[{"#name":"text" "_":"Emotional Facial Expression AUD"} {"#name":"keyword" "$":{"id":"kw0065"} "$$":[{"#name":"text" "_":"Alcohol Use Disorder RMET"} {"#name":"keyword" "$":{"id":"kw0075"} "$$":[{"#name":"text" "_":"Reading the Mind In The Eyes Test |
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