| 北五味子的镇静、催眠作用 |
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| 引用本文： | 霍艳双,陈晓辉,李康,毕开顺,王敏伟.北五味子的镇静、催眠作用[J].沈阳药科大学学报,2005,22(2):126-128. |
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| 作者姓名： | 霍艳双 陈晓辉 李康 毕开顺 王敏伟 |
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| 作者单位： | 沈阳药科大学,药学院,辽宁,沈阳,110016 |
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| 基金项目： | 辽宁省自然科学基金资助项目 (2 0 0 2 2 0 5 4 ) |
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| 摘 要： | 目的对北五味子水提取物镇静、催眠药理作用进行初探。方法采用镇静、催眠实验观察北五味子水提取物对小鼠自主活动的影响 ,协同戊巴比妥钠对小鼠的催眠作用。结果北五味子水提取物能明显减少小鼠自主活动次数 ,增加阈下剂量戊巴比妥钠致小鼠睡眠只数 ,延长阈上剂量戊巴比妥钠致小鼠睡眠时间。结论北五味子水提取物有明显的镇静、催眠作用。
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| 关 键 词： | 五味子 镇静 催眠 |
| 文章编号： | 1006-2858(2005)02-0126-03 |
| 修稿时间： | 2004年6月29日 |
Preliminary study on the sedative and hypnotic effects of the water extract of Fructus schisandrae Chinensis |
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| HUO Yan-shuang,CHEN Xiao-hui,LI Kang,BI Kai-shun,WANG min-wei.Preliminary study on the sedative and hypnotic effects of the water extract of Fructus schisandrae Chinensis[J].Journal of Shenyang Pharmaceutical University,2005,22(2):126-128. |
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| Authors: | HUO Yan-shuang CHEN Xiao-hui LI Kang BI Kai-shun WANG min-wei |
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| Abstract: | Objective To make a preliminary study on the sedative and hypnotic effects of the water extract of Fructus schisandrae Chinensis.Method Sedative and hypnotic experiments were made to observe the effects of the water extract of Fructus schisandrea Chinensis on spontaneous motion and hyponosis in mice.Results The results showed that the water extract of Fructus schisandrae Chinensis could markedly inhibit spontaneous motion,enhance the sleeping number of pentobarbital sodium (subthreshold dosage) and prolong the sleeping time of pentobarbital sodium (superthreshold dosage).Conclusion The water extract of Fructus schisandrae Chinensis possesses obvious sedative and hypnotic effects. |
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| Keywords: | Schisandra chinensis(Turcz ) Baill sedation hypnotism |
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