| 血清leptin、AsAb、EmAb检测在女性不孕不育症中的临床意义 |
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| 引用本文： | 罗健,周明连,孙刚,何浩明.血清leptin、AsAb、EmAb检测在女性不孕不育症中的临床意义[J].放射免疫学杂志,2010,23(3):267-269. |
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| 作者姓名： | 罗健 周明连 孙刚 何浩明 |
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| 作者单位： | 江苏省连云港市妇幼保健院,222006 |
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| 摘 要： | 目的：检测女性不明原因不孕、不育症血清瘦素（leptin）、AsAb、EmAb（均为IgG抗体）及其临床意义,为女性不明原因不孕不育症患者提供诊断和治疗依据。方法：临床选择32例女性不明原因不孕不育症患者应用放免法和ELISA进行血清leptin、AsAb、EmAb三项技术统计分析并与35名正常健康妇女作比较。结果：32例女性不明原因不孕不育症患者血清leptin水平均显著低于正常妇女组（P〈0.01）,而AsAb、EmAb两项阳性者占78.1%,EmAb阳性者占21.9%。结论：leptin水平低下和免疫因素为女性不明原因不孕不育症的主要原因。
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| 关 键 词： | 女性不孕不育 瘦素 抗精子抗体 抗子宫内膜抗体 |
Clinical Significance of Determination of Serum Leptin and AsAb, EmAb Levels in Infertile Women |
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| Luo Jian,Zhou Ming-lian,Sun Gang,et al..Clinical Significance of Determination of Serum Leptin and AsAb, EmAb Levels in Infertile Women[J].Journal of Radioimmanology,2010,23(3):267-269. |
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| Authors: | Luo Jian Zhou Ming-lian Sun Gang |
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| Institution: | Luo Jian,Zhou Ming-lian,Sun Gang,et al.Lianyungang Wormen and Children Health Hospital,Lianyungang(222006),China |
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| Abstract: | Objective To study the clinical significance of determination of serum leptin,AsAb,and EmAb levels in infertile women.Methods Serum leptin(with RIA)and AsAb,EmAb(with ELISA)levels were detected in 32 infertile women and 35 controls.Results Serum leptin levels in infertile women were significantly lower than those in controls(P<0.01).Serum AsAb and EmAb were both positive in 25 of the 32 infertile women(78.1%)and EmAb(one of two Abs)was positive in the rest 7 women(21.9%).These positive rates were also signi... |
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| Keywords: | infertile wormen leptim anti-sperm antibody(AsAb) endomential antibody(EmAb) |
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