| Abstract: | The whole-nerve action potential (AP) was recorded by intracochlear electrodes in the guinea-pig. As is well known, in normal conditions, the AP elicited by tone bursts displays negative and positive deflections. Inactivation of the central end of the nerve at the internal auditory meatus (IAM), by introduction of a few drops of KC1 solution, or by mechanical pressure, produces a change in the wave shape of AP which is transformed into a single negative deflection. The relation of the amplitude of the monophasic AP to the intensity of the tone burst is monotonic, in contrast to the classical two-slope variation observed in normal conditions. These results are interpreted by the disappearance of a positive component of the response produced at the IAM. The convolution of the monophasic unit AP would explain the monotonic intensity function. |
