涂片阴性肺结核化疗方案中加用迪克菲的研究

目的 为探讨一种高效稳定．简便易行．适用于现有条件下广泛应用于涂阴肺结核的短期化疗方案。方法 对120例初治涂阴肺结核病人．应用含迪克菲抗痨新药组成2HL1 ZE／2L1H化疗方案，采用不住院全程管理方法。结果 病灶吸收率为95．80％(115／120)；停药3年．随访观察肺部病灶X线复发率为5．83％(7/120)；没有1例痰菌复阳。结论 此化疗方案疗程短，疗效高．毒性小。费用低．而且近中期疗效都较满意．对落实“查实必治、治必彻底”的要求提供了有效办法．为在现有经济条件下尤其是农村推广应用化疗方案提供了希望和可能。

Study of Chemotherapy and Dikefi in Treating Smear Negative Pneumonia

Objective To investigate effective, stable,simple,short-course chemotherapy regimens in pulmonary tuberculosis with smear negative.Methods 120 cases of pulmonary tuberculosis with smear negative and initial treatment receive combined chemotherapy regimens 2HL 1 ZE/2L 1 H.Results The X-ray resolution rates was 95.80%(115 of 120),the 120 cases was follow-up visited three years after the therapy.The relapsing rates of X-ray performance were 5.83%(7 of 120).Sputum positive conversion were zero.Conclusion Our study showed that the combined chemotherapy regimens provide a new effective way for treatment of pulmonary tuberculosis.