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白癜风皮肤的反射光谱及其Monte Carlo模拟
引用本文:陈荣,曾海山,黄宝华,黄志伟,谢树森. 白癜风皮肤的反射光谱及其Monte Carlo模拟[J]. 中国生物医学工程学报, 2007, 26(1): 94-98
作者姓名:陈荣  曾海山  黄宝华  黄志伟  谢树森
作者单位:1. 福建师范大学,医学光电科学与技术教育部重点实验室,福州,350007
2. 加拿大BC癌研究中心,加拿大,温哥华,V5Z IL3
基金项目:教育部科学技术研究项目;福建省科技厅科研项目;福建省发改委科研项目;加拿大防癌协基金
摘    要:测试并研究了具有三种不同肤色的白癜风皮肤的反射光谱,在皮肤组织病理检验的基础上,建立了三色白癜风皮肤的光学模型,讨论了该皮肤的黑色素含量与分布,并进行Monle Carlo模拟计算。研究表明,白癜风皮肤,特别是具有不同肤色的白癜风,可作为一个较好的研究对象,用于探测皮肤黑色素分布或其他光学特性;反射光谱可用于皮肤表层黑色素的研究,特别是在表皮层黑色素缺失的情况下,可探知较深层(如真皮层)的黑色素含量与分布;采用Monte Carlo模拟,可以重现实测的皮肤光谱特性,并可预言皮肤组织中某些生化物质的存在。

关 键 词:三色白癜风  反射光谱  黑色素含量分布  Monte Carlo模拟
文章编号:0258-8021(2007)01-0094-04
收稿时间:2005-08-29
修稿时间:2006-07-09

Reflectance Spectrum of Vitiligo Skin and its Monte Carlo Simulation
CHEN Rong,ZENG Hai-Shan,HUANG Bao-Hua,HUANG Zhi-Wei,XIE Shu-Sen. Reflectance Spectrum of Vitiligo Skin and its Monte Carlo Simulation[J]. Chinese Journal of Biomedical Engineering, 2007, 26(1): 94-98
Authors:CHEN Rong  ZENG Hai-Shan  HUANG Bao-Hua  HUANG Zhi-Wei  XIE Shu-Sen
Abstract:Reflectance spectra of trichrome vitiligo skin were tested and studied,and optical models for trichrome vitiligo skin were developed on the basis of skin pathology.Skin melanin content and distribution were discussed and Monte Carlo simulation was made as well.The study suggests that(1)Vitiligo skin,especially the trichrome vitiligo skin could be an ideal object to detect skin melanin content and distribution or other skin optical properties;(2)Reflectance spectrum could be used to study depigment in skin surface,and especially with melanin depigment in skin surface,it could be used to test the melanin content and distribution in deeper layer(e.g.dermis);(3)Via Monte Carlo simulation,skin spectrum property could be reconstructed and some biochemical components in the skin tissue could be foreseen.
Keywords:trichrome vitiligo   reflectance spectrum   melanin content and distribution   Monte Carlo simulation
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