纳络酮治疗急性脑梗死临床疗效

目的 :观察纳络酮 (naloxone)治疗急性脑梗死的临床疗效。方法 :急性脑梗死 40例用纳络酮治疗 2个疗程后与 40例同样患者用复方丹参或维脑路通治疗对照 ,观察临床疗效及血液流变学指标变化 ,用 χ2 或u检验。结果 :治疗组的有效率为95 % ,高于对照组的 70 % (P <0 .0 5 ) ;治疗后血液流变学 5项指标治疗组明显改善 ,与对照组相比差异均有显著性 (P <0 .0 0 1)。结论 :纳络酮对急性脑梗死有明显疗效 ,是治疗本病的有效药物之一

Naloxone in treatment of acute cerebral infarction

Objective:To study the therapeutic effect of naloxone on acute cerebral infarction.Methods:Eighty patients were divided into two paralled groups.One was treated with naloxone and the other with Co Dansen or Venorouton as control.The therapeutic effect on changes of parameters associated with hemorrheology in the patients was observed.Chisguars of u test was used in the comparison.Results:The effective rate of treated group(95%) was much higher than that of control group(70%)( P <0.05).After treatment,the values of 5 parameters associated with hemorrheolgy in the treated group were significntly lower than that of the control group( P <0.001).Conclusions:Our studies show that naloxone is effective in treating acute cerebral infarction.