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| 以纳米分子探针为基础的分子影像技术在肿瘤早期检测中的应用 | |
| 引用本文： | 杨芳,吉民综述,顾宁.以纳米分子探针为基础的分子影像技术在肿瘤早期检测中的应用[J].中国医学影像技术,2009,25(2):316-318. |
| 作者姓名： | 杨芳 吉民综述 顾宁 |
| 作者单位： | 1. 东南大学生物科学与医学工程学院,生物电子学国家重点实验室,江苏,南京,210096;江苏省生物材料与器件重点实验室,江苏,南京,210009 2. 苏州生物医学材料技术重点实验室,江苏,苏州,215123;东南大学化学化工学院制药工程系,江苏,南京,210096 3. 东南大学生物科学与医学工程学院,生物电子学国家重点实验室,江苏,南京,210096;江苏省生物材料与器件重点实验室,江苏,南京,210009;苏州生物医学材料技术重点实验室,江苏,苏州,215123 |
| 基金项目： | 国家重大科学研究计划，国家自然科学基金 |
| 摘 要： | 包含纳米材料、纳米器件以及纳米表征测量等的纳米技术,对生物、医学的进步产生了巨大影响.尤其利用纳米材料独特的颗粒及光学、电学等特性,结合现代医学影像技术,如光学成像、CT、PET/SPECT、MRI及超声成像(US)等,有可能在肿瘤发生初期进行早期特异性检测和有效的靶向治疗,使影像医学从对传统的解剖和生理功能的研究进展到分子水平成像,实现靶向分子成像,探索疾病的分子水平变化,在疾病早期做出明确诊断. |
| 关 键 词： | 纳米粒子 分子影像 探针 肿瘤 早期诊断 |
| 收稿时间： | 7/2/2008 12:00:00 AM |
| 修稿时间： | 2008/11/4 0:00:00 |
Nanoparticles probe for targeted molecular imaging in early detection of cancer |
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| YANG Fang,JI Min and GU Ning.Nanoparticles probe for targeted molecular imaging in early detection of cancer[J].Chinese Journal of Medical Imaging Technology,2009,25(2):316-318. | |
| Authors: | YANG Fang JI Min and GU Ning |
| Institution: | State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China;Jiangsu Laboratory for Biomaterials and Devices, Nanjing 210009, China;Suzhou Key Laboratory of Biomedical Materials and Technology, Suzhou Institute of Southeast University, Suzhou 215123, China;State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China |
| Abstract: | Nowadays, nanotechnology, such as nano-materials, nano-devices and nano-characterization technology, has greatly influenced biological and medical development. Especially, the nanoparticles have unique size, optical and electronic characteristics. Combing nanoparticle-based molecular probe with the medical imaging technology, the cancer can be detected at very early stage by specific detection and effective targeted therapy will be performed accordingly. In this way, medical imaging changes from the study of conventional anatomy and physiology to molecular imaging, which makes targeted molecular therapy and early detection of tumor into reality. |
| Keywords: | Nanoparticles Molecular imaging Probe Neoplasms Early diagnosis |
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