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Immunization with Recombinant Surface Antigen P50 of Babesia gibsoni Expressed in Insect Cells Induced Parasite Growth Inhibition in Dogs |
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| Authors: | Shinya Fukumoto Yoh Tamaki Hiroaki Shirafuji Shinji Harakawa Hiroshi Suzuki Xuenan Xuan |
| Affiliation: | National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido,1 The Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Hongo, Bunkyo-ku,2 Research & Development Department, Hakujyu Institute for Health Science Co., Ltd., Tomigaya, Shibuya-ku, Tokyo, Japan3 |
| Abstract: | This is a report of a vaccine trial directed against Babesia gibsoni infection in dogs with the use of the recombinant antigen P50. Dogs immunized with P50 showed partial protection manifested as a significantly low level of parasitemia. The results indicated that P50 is a primary vaccine candidate molecule against canine B. gibsoni infection. |
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