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| 体外循环对循环巨核细胞和血小板的影响及意义 | |
| 引用本文： | 赵初环,林洁,钱红兰,冯霞飞,张翔,孙成超.体外循环对循环巨核细胞和血小板的影响及意义[J].中国现代医生,2011,49(15):144-145,151. |
| 作者姓名： | 赵初环 林洁 钱红兰 冯霞飞 张翔 孙成超 |
| 作者单位： | 1. 温州医学院附属第一医院心脏监护室,浙江温州,325000 2. 温州医学院附属第一医院呼吸内科,浙江温州,325027 3. 温州医学院附属第一医院血液内科,浙江温州,325000 4. 温州医学院附属第一医院心胸外科,浙江温州,325000 |
| 基金项目： | 浙江省温州市科技计划项目;项目 |
| 摘 要： | 目的 探讨体外循环（CPB）对循环巨核细胞和血小板的影响及意义。方法观察测定20例患者体外循环（CPB）前后巨核细胞、血小板计数（PLT）值变化，探讨体外循环（CPB）对循环巨核细胞和血小板的影响及意义。结果手术前、中、后中心静脉血的巨核细胞和4-型巨核细胞数量总数量高于同期周围动脉血的细胞总数量。体外循环中中心静脉血巨核细胞和4-型巨核细胞数量比术前和术后均升高，体外循环中血小板数量比术前和术后均降低（P〈0．01）。结论体外循环可以导致巨核细胞和血小板数量的改变，循环巨核细胞可能在肺中被破坏、损耗；急性肺损伤可能影响血小板数量。 |
| 关 键 词： | 体外循环 巨核细胞 血小板 |
Cardiopulmonary Bypass's Influence on Megakaryocytes and Platelet in Circulation |
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| Authors: | ZHAO Chuhuan LIN Jie QIAN Honglan FENG Xiafei ZHANG Xiang SUN Chengchao |
| Institution: | ZHAO Chuhuan1 LIN Jie2 QIAN Honglan3 FENG Xiafei1 ZHANG Xiang4 SUN Chengchao4 1.Department of CICU,the First Affiliated Hospital of Wenzhou Medical College,Wenzhou 325000,China,2.Department of Respiratory,Wenzhou 325027,3.Department of Hematology,4.Department of Cardiovascular Surgery |
| Abstract: | Objective To explore cardiopulmonary bypass's influence on platelet and megakaryocytes.Methods Megakaryocytes and platelet count(PLT)in 20 patients before and after cardiopulmonary bypass(CPB)were measured.To explore cardiopulmonary bypass's influence on platelet and megakaryocytes.Results The total number of megakaryocytes and 4-type of megakaryocytes in venous blood were higher than the same arterial blood.The total number of megakaryocytes and 4-type of megakaryocytes in venous blood within CPB were high... |
| Keywords: | Cardiopulmonary bypass Megakaryocyte Platelet |
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