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白花蛇舌草化学成分的研究
引用本文:吴孔松,张坤,谭桂山,曾光尧,周应军.白花蛇舌草化学成分的研究[J].中国药学杂志,2005,40(11):817-818.
作者姓名:吴孔松  张坤  谭桂山  曾光尧  周应军
作者单位:中南大学药学院药物化学系,湖南,长沙,410013
摘    要: 目的对白花蛇舌草的化学成分进行研究。方法采用聚酰胺、Sephadex LH-20和硅胶等多种色谱柱进行分离;理化性质,光谱数据鉴定结构。结果分离鉴定5个化合物:穗花衫双黄酮(Ⅰ),2-羟基-1-甲氧基蒽醌(Ⅱ),2.羟基-1,3-二甲氧基蒽醌(Ⅲ),香豆酸(Ⅳ)和E-6-O-香豆酰鸡屎藤苷甲酯(Ⅴ) 结论化合物Ⅰ,Ⅱ和Ⅲ为首次从该种植物中得到。

关 键 词:白花蛇舌草
文章编号:1001-2494(2005)11-0817-03
收稿时间:2004-08-05;

Studies on constituents of Oldenladia diffusa
WU Kong-song,ZHANG Kun,TAN Gui-shan,ZENG Guang-yao,ZHOU Ying-Jun.Studies on constituents of Oldenladia diffusa[J].Chinese Pharmaceutical Journal,2005,40(11):817-818.
Authors:WU Kong-song  ZHANG Kun  TAN Gui-shan  ZENG Guang-yao  ZHOU Ying-Jun
Institution:Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Central South University,Changsha 410013,China
Abstract:OBJECTIVE To investigate the chemical constituents of Oldenladia diffusa (Willd.) Roxb.. METHODS Polyamide column, Sephadcx LH-20 column and silica gel column et al, were used to separate and purify the chemical components. The structures were elucidated on the basis of physic-chemical properties and spectral data. RESULTS Five compounds were isolated and identified as amentoflavone (Ⅰ), 2-hydroxy-l-tnethoxyanthraquinone (Ⅱ), 1, 3-dimethoxy-2-hydroxyanthraquinone ( Ⅲ ), p-coumaric acid ( Ⅳ ) and E-6-O-p-coumaroyl scandoside methyl-ester(Ⅴ) .CONCLUSION Compound Ⅰ,Ⅱ and Ⅲ were obtained from this plant for the first time.
Keywords:Oldenladia diffusa(Willd  ) Roxb    chemical constituents
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