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| 取代4-吡啶酮-2-甲醛与氨基化合物缩合产物的合成及抗癌活性研究 | |
| 引用本文： | 唐磷,胥佩菱.取代4-吡啶酮-2-甲醛与氨基化合物缩合产物的合成及抗癌活性研究[J].华西药学杂志,1988(1). |
| 作者姓名： | 唐磷 胥佩菱 |
| 作者单位： | 华西医科大学药学院 成都 (唐磷)，华西医科大学药学院 成都(胥佩菱) |
| 基金项目： | 国家自然科学基金资助的课题 |
| 摘 要： | 本文合成了八个取代4-吡啶酮-2-甲醛与氨基化合物缩合产物,均未见诸文献;并进行了体外抗人胃癌细胞SGC7901和小鼠骨髓瘤细胞SP 2/0增殖能力影响的试验,都无明显活性。 |
| 关 键 词： | 3-甲氧基-4-吡啶酮-2-甲醛芳磺酰腙 3-甲氧基-4-吡啶酮-2-甲醛羧酰腙 3-甲氧基-4-吡啶酮-2-甲醛缩氨脲 人胃癌细胞SGC7901 小鼠骨髓瘤细胞SP2/0. |
STADY OF THE SYNTHESIS AND ANTINEOPLASTIC ACTIVITY OF THF CONDENSATING PRODUCTS OF 3-METHOXY-4-PYRIDONE-2-ALDEHYDE WITH AMINODERIVATIVES |
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| Tang Ling Xu Peilng.STADY OF THE SYNTHESIS AND ANTINEOPLASTIC ACTIVITY OF THF CONDENSATING PRODUCTS OF 3-METHOXY-4-PYRIDONE-2-ALDEHYDE WITH AMINODERIVATIVES[J].West China Journal of Pharmaceutical Sciences,1988(1). | |
| Authors: | Tang Ling Xu Peilng |
| Abstract: | Eight new condensating producfs of 3-methoxy-4-pyridone-2-aldehyde with aminoderivatives were synthesized, Their structures were confirmed by IR spectrometric cidentification and elementary analysis. Tested against, SGC-7901 and SP 2/0 in vitro. There was no one to show antineoplasttc activity. |
| Keywords: | 5-methoxy-4-pyredone-2-aldehyde arylsulfonylhydrazones 5-methoxy-4-pyredone-2-aldehyde semicarbazone 5-methoxy-4-pyredone-2-aldehyde hydrazone SGC-7901 SP 2/0 Antineoplastic Activity |
| 本文献已被 CNKI 等数据库收录！ | |