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A Study on Changes of the Plasma Endothelin Level in Patients with Dilated Cardiomyopathy
作者姓名:黄凯  朱树雄  尹瑞兴
作者单位:Department of Cardiology,First Affiliated Hospital of Guangxi Medical University,Nanning 530021,PR China.,Department of Cardiology,First Affiliated Hospital of Guangxi Medical University,Nanning 530021,PR China.,Department of Cardiology,First Affiliated Hospital of Guangxi Medical University,Nanning 530021,PR China.
摘    要:Objectives To evaluate the changes of the plasma endothelin level in patients with dilated cardiomyopathy, and to investigate the relationship between the plasma endothelin level and the severity of heart failure, heart size, left ventricular function and with or not with pulmonary arterial hypertension; the changes of the plasma endothelin level before and after treatment. Methods The plasma endothelin level of 30 patients with DCM, 30 healthy control subjects, and their LVEF, PAP, heart size, plasma endothelin level before and after treatment were determined. Results The plasma endothelin level in DCM group was significantly higher than that in control group ( 135.93 ± 70. 65pg/mL) vs(43.65 ± 12.07pg/mL), P < 0.05 ; there was a correlation between ET level and heart size ( r = O. 4580, P = 0. 0109 ) ; there was a significant negative correlation between LVEF of DCM and ET level( r = -0. 6922 ,P =0. 0021 ) ;and it was a significant positive correlation between ET level and pulmonary arterial hyperten

关 键 词:扩张型心肌病  内皮素  血浆  临床意义  肺动脉高压

A Study on Changes of the Plasma Endothelin Level in Patients with Dilated Cardiomyopathy
HUANG kai,ZHU Shuxiong YIN Ruixing.A Study on Changes of the Plasma Endothelin Level in Patients with Dilated Cardiomyopathy[J].South China Journal of Cardiology,2003,4(2):93-96.
Authors:HUANG kai  ZHU Shuxiong YIN Ruixing
Institution:HUANG kai,ZHU Shuxiong YIN Ruixing Department of Cardiology,First Affiliated Hospital of Guangxi Medical University,Nanning 530021,PR China.
Abstract:
Keywords:Dilated cardiomyopathy Endothelin
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