| 人参子注射液对维拉帕米致犬急性心力衰竭心功能的影响 |
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| 引用本文： | 徐凤芹,史大卓,孟亮.人参子注射液对维拉帕米致犬急性心力衰竭心功能的影响[J].中西医结合心脑血管病杂志,2003,1(2):63-65. |
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| 作者姓名： | 徐凤芹 史大卓 孟亮 |
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| 作者单位： | 1. 中国中医研究院西苑医院心血管科,100091
2. 中国医学科学院阜外医院 |
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| 摘 要： | 目的：观察人参子注射液对急性心力衰竭犬心功能的影响。方法：采用健康杂种犬静脉输注维拉帕米（异搏定）造成急性心力衰竭动物模型。静脉给予不同剂量的人参子注射液，观察用药前后左心室内压上升最大速率（dp/dtmax)。左心室舒张终末压（LVEDP）及心排血量（CO）的变化。结果：各组造模后dp/dt-max,CO均明显下降，LVEDP升高，用人参子注射液治疗后即刻dp/dtmax虽有所下降，但随后逐渐回升，LVEDP下降，CO增加。结论：人参子注射液可明显降低心脏前负荷，改善心脏的收缩功能。增加心输出量。
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| 关 键 词： | 人参子注射液 急性心力衰竭 心功能 |
| 文章编号： | 1672-1349(2003)02-0063-03 |
| 修稿时间： | 2002年12月10 |
Effect of Ginseng Fruit Injection on Cardiac Function of Acute Heart- Failure Dog Induced by Verapamil |
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| Xu Fengqin,Shi Dazhuo,Meng liang//Cardiovascular Division,Xiyuan Hospital of China Academy of T C M.Effect of Ginseng Fruit Injection on Cardiac Function of Acute Heart- Failure Dog Induced by Verapamil[J].Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease,2003,1(2):63-65. |
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| Authors: | Xu Fengqin Shi Dazhuo Meng liang//Cardiovascular Division Xiyuan Hospital of China Academy of T C M |
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| Institution: | Beijing 100091 |
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| Abstract: | Objective:To observe effects of ginseng fruit injection on cardiac function of acute heart-failure dog.Methods:Acute heart-failure model was made by injecting verapamil in healthy dog. Ginseng fruit injection was ivgtt in different dosage.To observe dp/dtmax and CO of left ventricle before and after using injection.Results:dp/dtmax and CO decreased ,but LVEDP increased in every group after model forming.After treatment with ginseng fruit injection,although dp/dtmax slightly decreased immediately,dp/dtmax would gradually rise again.LVEDP decreased.CO increased.Conclusion:Ginseng fruit injection could decrease heart preload obviously,improre contraction of heart,CO adding and increase CO. |
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| Keywords: | Ginseng fruit injection Acute heart-failure Cardiac function |
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