Health-related quality of life after mandibular resection for
oral cancer: Reconstruction with free fibula flap |
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Authors: | Wenli Yang Sanjun Zhao Fei Liu Minglei Sun |
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Institution: | 1.Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou,China;2.Deparrtment of Prosthodontics, School of Stomatology, Fourth Military Medical University. Xi´an, China |
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Abstract: | Objectives: Mandibular resection for oral cancer is often necessary to achieve an adequate margin of tumor clearance. Mandibular resection has been associated with a poor health-related quality of life (HRQOL), particularly before free fibula flap to reconstruct the defect. The aim of this study was to evaluate health-related quality of life in patients who have had mandibular resections of oral cancer and reconstruction with free fibula flap.
Study Designs: There were 115 consecutive patients between 2008 and 2011 who were treated by primary surgery for oral squamous cell carcinoma, 34 patients had a mandibular resection. HRQOL was assessed by means of the 14-item Oral Health Impact Profile (OHIP-14) and University of Washington Quality of Life (UW-QOL) questionnaires after 12 months postoperatively.
Results: In the UW-QOL the best-scoring domain was mood, whereas the lowest scores were for chewing and saliva. In the OHIP-14 the lowest-scoring domain was social disability, followed by handicap, and psychological disability.
Conclusions: Mandible reconstruction with free fibula flap would have significantly influenced on patients’quality of life and oral functions. The socio-cultural data show a fairly low level of education for the majority of patients.
Key words:Health-related quality of life, free fibula flap, mandibulectomy, UW-QOL, OHIP-14. |
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