Safety and efficacy of the Yukon Choice Flex sirolimus-eluting coronary stent in an all-comers population cohort |
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Authors: | E. Xhepa T. Tada S. Cassese L. King I. Ott M. Fusaro A. Kastrati R.A. Byrne |
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Affiliation: | Deutsches Herzzentrum, Technische Universität, Lazarettstrasse 36, 80636 Munich, Germany |
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Abstract: | AimsThe use of biodegradable-polymer drug-eluting stents has been shown to provide favorable results when compared with durable polymer drug-eluting stents and long-term follow up data have recently shown significant reductions in terms of very late stent thrombosis.Aim of the present study was to assess the safety and efficacy profile of a novel biodegradable polymer DES, the Yukon Choice Flex sirolimus-eluting stent.MethodsWe report here the one-year clinical outcomes associated with the use of the Yukon Choice Flex sirolimus-eluting stent in an all-comers patient population. The present stent represents a further refinement of the stent platform tested in the ISAR TEST 3 and 4 randomized clinical trials. A total of 778 consecutive patients undergoing implantation of this stent were enrolled in the present observational study and prospectively followed for one year.ResultsThe use of the Yukon Choice Flex stent in a patient population with complex coronary lesion morphology was associated with optimal immediate angiographic results. At one year follow up the rates of death, myocardial infarction, definite stent thrombosis and ischemia-driven target lesion revascularization were respectively 2.4%, 1.9%, 0.3% and 11.3%.ConclusionsThe use of the sirolimus-eluting biodegradable polymer Yukon Choice Flex stent in an all-comers population of patients with complex coronary artery disease is associated with a favorable safety and efficacy profile up to one year follow up. |
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Keywords: | Percutaneous coronary intervention Bioresorbable-polymer drug-eluting stent Stent thrombosis |
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