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Lymphoblastoid Cell Lines of Homozygous Typing Cells Used for Sensitization in PLT |
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| Authors: | Nancy Reinsmoen Edmond J. Yunis Fritz H. Bach Marilyn L. Bach |
| Affiliation: | Department of Laboratory Medicine and Pathology University of Minnesota Medical School Minneapolis, Minnesota, U.S.A.;The Immunobiology Research Center and Departments of Medical Genetics, Surgery and Pediatrics University of Wisconsin Madison, Wisconsin, U.S.A. |
| Abstract: | Lymphoblastoid cell lines of homozygous typing cells were used as the sensitizing cells in MLC to prepare PLT cells. Results obtained using such cells against a panel of restimulating cells were compared to those obtained using regular PLT cells in which priming had been accomplished with normal peripheral blood lymphocytes. It appears that lymphoblastoid cell lines can be used for this purpose; the advantages of such an approach are given. |
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