| 阿普唑仑与米帕明治疗抑郁性神经症的对照试验 |
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| 引用本文： | 潘腾苏,张宏根,郝伟. 阿普唑仑与米帕明治疗抑郁性神经症的对照试验[J]. 中国新药与临床杂志, 1993, 0(6) |
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| 作者姓名： | 潘腾苏 张宏根 郝伟 |
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| 作者单位： | 湖南省精神病医院，湖南省精神病医院，湖南医科大学精神卫生研究所 长沙 410007，长沙 410007，长沙 410011 |
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| 摘 要： | 报道阿普唑仑(男性16,女性14,年龄30.1±s 1.9a,剂量2.4mg±1.2mg/d,6wk)和米帕明(男性14,女性12,年龄28.2±1.7a,剂量175mg±25mg/d,6wk)治疗抑郁性神经症56例的对照试验。结果2组治疗前到结束HAMD,SDS总分降低差别显著(P<0.01),而药物显效时间、治疗总有效率2组差别不显著。TESS评分阿普唑仑的不良反应显著少于米帕明。
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| 关 键 词： | 阿普唑仑 米帕明 抑郁障碍症 |
Alprazolam vs imipramifie in treating depressive neurosis |
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| PAN Teng-Su,ZHANG Hong-Gen. Alprazolam vs imipramifie in treating depressive neurosis[J]. Chinese Journal of New Drugs and Clinical Remedies, 1993, 0(6) |
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| Authors: | PAN Teng-Su ZHANG Hong-Gen |
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| Abstract: | This paper reports a control trial of alprazolam (M 16, F 14, age 30.1 ±s1.9a, dose 2.4mg ± 1.2mg/d,6wk) vs imipramine (M 14, F 12, age 28.2 ± 1.7a, dose 175mg ± 25mg/d, 6wk)in treating patients with depressive neurosis. At the end of therapy, the total scores on HAMD and SDS of both groups decreased (F<0. 01). The period from taking drugs to emergence of antidepressive effects and total response rates did not show significant differences between the 2 groups. TESS test showed that adverse reactions of alprazolam were less than those of imipramine. |
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| Keywords: | alprazolam imipramine depressive disorder |
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