经皮穿刺三叉神经半月节射频热凝加得宝松注射治疗原发性三叉神经痛

目的：探讨经皮穿刺三叉神经半月节射频热凝加得宝松注射治疗原发性三叉神经痛的临床疗效。方法：原发性三叉神经痛患者151例,随机分为观察组76例和对照组75例,观察组采用Hartel前入路穿刺法,在CT引导下经皮穿刺三叉神经半月节射频热凝加得宝松注射治疗。对照组采取单纯内科药物治疗。结果：观察组1次射频治疗后达显效54例、有效19例;对照组治疗10 d后,显效及有效分别为47例、17例,观察组总有效率明显高于对照组（96.1%、85.3%,P〈0.05）。随访0.5-2年,观察组复发率明显低于对照组（5.6%、36.2%,P〈0.05）。结论：CT引导下经皮穿刺三叉神经半月节射频热凝加得宝松注射能明显缓解原发性三叉神经痛的临床症状,降低复发率。

Clinical Effectiveness of Percutaneous Semilunar Ganglion Radiofrequency Thermo-coagulation (RFT) and Diprospan Injection Treating Primary Trigeminal Neuralgia

Objective: To study the clinical effectiveness of percutaneous semilunar ganglion radiofrequency thermo-coagulation(RFT) in combination with Diprospan injection in the treatment of primary trigeminal neuralgia.Methods: 151 cases of primary trigeminal neuralgia were randomly divided into treatment group(76 cases) and control group(75 cases),receiving percutaneous semilunar ganglion RFT and Diprospan injection through the Hartel anterior approach under the CT guidance,and single medication,respectively.Results: After one treatment of RFT in treatment group,54 cases and 19 cases obtained apparent effectiveness and effectiveness respectively,and in control group,47 and 17 cases obtained apparent effectiveness and effectiveness respectively after treatment for 10 days.The overall effective rate in treatment group was significantly higher than in control group(96.1% vs 85.2%,P<0.05).After follow up for 0.5 to 2 years,the recurrent rate in treatment group was significantly lower than in control group(5.6% vs 36.2%,P<0.05).Conclusion: Percutaneous semilunar ganglion RFT in combination with Diprospan injection under CT guidance is an effective therapy to treat primary trigeminal neuralgia.