晚期早产儿的临床回顾分析

目的 研究晚期早产儿存在的临床问题.方法 回顾性总结我院新生儿病房及新生儿监护病房2007年9月至2008年9月收治的晚期早产儿508例、足月儿1 514例的临床资料.记录低体温、呼吸窘迫、暂时性呼吸增快、低血糖、黄疸、颅内出血的发生率及临床转归.结果 与足月儿相比.晚期早产儿低体温(13.4%vs 0)、低血糖(19.9%vs 3.0%)、呼吸窘迫(38.6%vs 10.8%)、暂时性呼吸增快(31.0%vs 13.1%)、颅内出血(5.1%vs 2.3%)、黄疽(55.0%vs 33.0%)及喂养不耐受(52.4%vs 14.2%)的发生率高,差异有非常显著性(P＜0.01).晚期早产儿接受机械通气、应用肺表面活性物质和经鼻持续气道正压通气呼吸支持的比例高于足月儿(P＜0.05,P＜0.01).晚期早产儿未完成治疗的比例高于足月儿(P＜0.01).结论 晚期早产儿比足月儿存在更多的临床问题,是不应被忽视的高危人群.

Retrospective survey on health issues of late preterm infants

Objective To analyze if late preterm infants have more postnatal health issues than full term infants.Methods Two thousands four hundreds and ten neonatal records were reviewed from August 31st 2007 to September 1st 2008.There were totally 508 late preterm and 1 514 full term infants were admitted during that time.The incidence of hypothermia,jaundice,hypoglycemia,transient tachypnea of newborn,feeding difficulties,respiratory distress and intracranial hemorrhage was collected.Clinical prognosis was analyzed.Results The incidence of hypothermia was significantly higher in late preterm infants group as compared to full term infants group(13.4% vs 0),same as hypoglycemia(19.9% vs 3.0%,P ＜0.01),respiratory distress(38.6% vs 10.8%,P ＜ 0.01),jaundice(55.0% vs 33.0%,P ＜ 0.01),feeding difficulties (52.4% vs 14.2%,P ＜0.01),transient tachypnea of newborn(31.0% vs 13.1%,P ＜0.01)and intracranial hemorrhage(5.1% vs 2.3%,P ＜0.01).The proportion of ventilation,the usage of surfactant and nasal continuous positive airway pressure were higher in late preterm infants group and the withdrawal rate was also higher as compared to full term infants group.Conclusion Late preterm infants have more complications versus full term infants and it has potential unrecognized risk among neonatal population.