Noopept pharmacokinetics after intravenous administration of a lyophilized medicinal form in rats |
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| Authors: | S. S. Boiko V. P. Zherdev V. P. Kolyvanov R. U. Ostrovskaya T. A. Gudasheva K. S. Us S. B. Seredenin |
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| Affiliation: | (1) Zakusov Institute of Pharmacology, Russian Academy of Medical Sciences, Moscow, Russia |
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| Abstract: | The pharmacokinetics of noopept, a dipeptide drug possessing nootropic and neuroprotective properties, were evaluated in rats after the intravenous administration of its novel formulation for injections prepared using lyophilization in the presence of mannitol. The pharmacokinetic characteristics of the new preparation are comparable with those of aqueous solutions of the parent substance and can be recommended for further investigation and implementation into medical practice. __________ Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 41, No. 3, pp. 6–8, March, 2007. |
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