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P300对注意缺陷多动障碍儿童哌甲酯治疗的疗效预评价
引用本文:盛未,杨玉霞,董选.P300对注意缺陷多动障碍儿童哌甲酯治疗的疗效预评价[J].实用儿科临床杂志,2005,20(11):1128-1129.
作者姓名:盛未  杨玉霞  董选
作者单位:1. 苏州大学附属第三医院儿科,江苏,常州,213003
2. 苏州大学附属第三医院电生理试验室,江苏,常州,213003
基金项目:国家自然科学基金项目资助(30470566)
摘    要:目的探讨注意缺陷多动障碍(ADHD)儿童服用哌甲酯治疗前后认知电位(P300)变化,以此指标指导ADHD儿童治疗。方法对22例ADHD儿童采用视觉诱发电位刺激,检测其服用哌甲酯治疗前后脑视觉诱发电位P300潜伏期和波幅变化。结果服用哌甲酯后P300潜伏期明显缩短(P<0.01),波幅变化无差异(P>0.05)。结论ADHD儿童服用哌甲酯前后P300潜伏期变化可指导临床ADHD儿童治疗。

关 键 词:注意缺陷多动障碍  哌甲酯  P300
文章编号:1003-515X(2005)11-1128-02
收稿时间:2005-09-24
修稿时间:2005年9月24日

Pre-evaluation of Effect of Litalin in Children with Attention Deficit/Hyperactivity Disorder by P300
SHENG Wei,YANG Yu-xia,DONG Xuan.Pre-evaluation of Effect of Litalin in Children with Attention Deficit/Hyperactivity Disorder by P300[J].Journal of Applied Clinical Pediatrics,2005,20(11):1128-1129.
Authors:SHENG Wei  YANG Yu-xia  DONG Xuan
Institution:1. Department of Pediatrics;2. Laboratory of Electric Physiology, the Third Hospital Affiliated to Suzhou Univerisity, Changzhou 213003, China
Abstract:Objective To investigate the change of P300 of the attention - deficit/hyperactivity disorder children before and after they took litalin, according to this objective subject to guide the clinical treatment of ADHD children. Methods Using the looking se-ducible electricity stimulates 22 ADHD children, and check the change of latency and the rate of the wave before and after they took litalin. Results After ADHD children took litalin, their latency of P300 has decreased clearly, and the amplitude had no change. Conclusion The changes of P300 latency in ADHD children after they took litalin can be adopted as the guidelines of clinical treatment for the ADHD children.
Keywords:attention - deficit/hyperactivity disorder  litalin  P300
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