泌尿生殖道支原体感染及药敏分析

目的 了解本市解脲支原体(Uu)和人型支原体(Mh)引起泌尿生殖道感染的状况,为临床治疗支原体感染的抗生素选择提供参考依据.方法 采用支原体培养、鉴定、药敏一体化单浓度试剂盒进行检测.结果 门诊送检11 997例标本,支原体培养阳性共5 517例(46.0%),其中单纯Uu感染4 608例(38.4%),单纯Mh感染331例(2.8%),Uu与Mh双重感染578例(4.8%).药敏试验结果显示,Uu对甲砜霉素、克拉霉素、阿奇霉素的耐药率分别为2.0%、2.6%、4.5%,Mh对甲砜霉素、交沙霉素、克拉霉素的耐药率分别为7.6%、8.5%、8.8%.结论 泌尿生殖道支原体感染以Uu感染为主,甲砜霉素、克拉霉素为治疗首选药物.

Analysis on mycoplasma infection of urogenital tract and drug susceptibility

Objective To investigate the infection statue of Ureaplasma urealyticum (Uu) and Mycoplasma hominis (Mh) in patients with urogenital tract infection and so as to instruct drug selecting in clinical treatment.Methods Mycoplasma culture,identification and sensitivity test kit was applied to detecting Uu, Mh and their sensitivety to antimicrobial drugs.Results Among 11 997 cases of samples, 5 517 cases were mycoplasma positive (46.0%). 4 608 cases were only infected by Ureaplasma urealyticum (Uu) (38.4%), 331 cases were only infected by Mycoplasma hominis (Mh) (2.8%), and 578 cases were infected by Uu Mh (4.8%). The results of antimicrobial susceptibility test showed that the drug resistance of Uu to thiamphenicol, clarithromycin and azithromycin was 2.0%, 2.6% and 4.5% respectively; the drug resistance of Mh to thiamphenicol, josamycin and clarithromycin was 7.6%, 8.5% and 8.8% respectively.Conclusion The major mycoplasma is Uu in urogenital tract infection. Thiamphenicol and clarithromycin may be the first choice to treat mycoplasma infection.